Evidence map›Paper›PMID 36934344›Full record

ArticleEnvironmental science & technology2023

Sensing Antibiotics in Wastewater Using Surface-Enhanced Raman Scattering.

Yen-Hsiang Huang, Hong Wei, Peter J Santiago, William John Thrift, Regina Ragan, Sunny Jiang

Abstract read
In one paragraph

Article in Environmental science & technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Quantum vibropolaritonic sensing.Science advances · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Multiplexed SERS Detection of Serum Cardiac Markers Using Plasmonic Metasurfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yen-Hsiang HuangDepartment of Civil and Environmental Engineering, University of California, Irvine, Irvine, California 92697, United States.
Hong WeiDepartment of Materials Science and Engineering, University of California, Irvine, Irvine, California 92697, United States.
Peter J SantiagoDepartment of Materials Science and Engineering, University of California, Irvine, Irvine, California 92697, United States.
William John ThriftDepartment of Materials Science and Engineering, University of California, Irvine, Irvine, California 92697, United States.
Regina RaganDepartment of Materials Science and Engineering, University of California, Irvine, Irvine, California 92697, United States.ORCID 0000-0002-8694-5683
Sunny JiangDepartment of Civil and Environmental Engineering, University of California, Irvine, Irvine, California 92697, United States.ORCID 0000-0002-4993-8038

Funding

DIABETIC UPPER EXTREMITY PATHOPHYSIOLOGY, LIMITED JOINT MOBILITY AND DISABILITYR21DK100793 · NIDDK · WASHINGTON UNIVERSITY · PI MUELLER, MICHAEL J · 2014 to 2015
$419k
NIDDK NIH HHS R21 DK100793
6 · The paper itself

Abstract

Rapid and cost-effective detection of antibiotics in wastewater and through wastewater treatment processes is an important first step in developing effective strategies for their removal. Surface-enhanced Raman scattering (SERS) has the potential for label-free, real-time sensing of antibiotic contamination in the environment. This study reports the testing of two gold nanostructures as SERS substrates for the label-free detection of quinoline, a small-molecular-weight antibiotic that is commonly found in wastewater. The results showed that the self-assembled SERS substrate was able to quantify quinoline spiked in wastewater with a lower limit of detection (LoD) of 5.01 ppb. The SERStrate (commercially available SERS substrate with gold nanopillars) had a similar sensitivity for quinoline quantification in pure water (LoD of 1.15 ppb) but did not perform well for quinoline quantification in wastewater (LoD of 97.5 ppm) due to interferences from non-target molecules in the wastewater. Models constructed based on machine learning algorithms could improve the separation and identification of quinoline Raman spectra from those of interference molecules to some degree, but the selectivity of SERS intensification was more critical to achieve the identification and quantification of the target analyte. The results of this study are a proof-of-concept for SERS applications in label-free sensing of environmental contaminants. Further research is warranted to transform the concept into a practical technology for environmental monitoring.

Indexed as

Metal NanoparticlesWastewaterGoldLimit of DetectionSpectrum Analysis, RamanGoldWastewaterquinolineSelf-Assembled SERS substrateSERSSERStrate

Identifiers

PMID36934344
PMCPMC10061928

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.