Evidence map›Paper›PMID 36934289›Full record

ArticleBMC women's health2023

Impact of (recurrent) bacterial vaginosis on quality of life and the need for accessible alternative treatments.

Karen Chow, Darcy Wooten, Sindhuja Annepally, Leah Burke, Rina Edi, Sheldon R Morris

Open access · goldFull text read
In one paragraph

Article in BMC women's health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. The Vaginal Microbiome: Setting the Stage for Cancer?The Journal of infectious diseases · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Bacterial vaginosis.Nature reviews. Disease primers · 2025
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Effects ofYonsei medical journal · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Karen ChowDepartment of Medicine, University of California San Diego, San Diego, CA, USA.
Darcy WootenDepartment of Medicine, University of California San Diego, San Diego, CA, USA.
Sindhuja AnnepallyDepartment of Medicine, University of California San Diego, San Diego, CA, USA.
Leah BurkeDepartment of Medicine, University of California San Diego, San Diego, CA, USA. lbburke@health.ucsd.edu.
Rina EdiDepartment of Medicine, University of California San Diego, San Diego, CA, USA.
Sheldon R MorrisDepartment of Medicine, University of California San Diego, San Diego, CA, USA.
University of California, San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBacterial vaginosis (BV) is one of the most common vaginal dysbiosis in women aged 15-44 years old.

methodsWe administered a cross-sectional, single timepoint survey to women ages 18 years or older and who have had bacterial vaginosis (BV). Women completed an anonymous online survey evaluating the impact of BV on their quality of life, how effective different types of treatments were and the amount of self-diagnosed vs. provider diagnosed BV episodes they had.

results62 participants completed the anonymous online survey. With a self-reported median number of BV episodes in the past year was 4 (IQR 1-7). Among these women 69.8% reported BV had a negative impact on their sexual health, 67.7% on their physical health, 74.6% on their mental health. More than half of the respondents had used probiotics with oral Lactobacillus sp. (53.2%), mainly by oral route, and over a third had used vaginal boric acid (37.1%). Most women were unaware of Lactobacillus crispatus. Lactobacillus probiotics were more likely to be tried by women who were negatively impacted by BV for overall quality of life (p = 0.033), sexual health (p = 0.002), and mental health (p = 0.006) while boric acid use was more likely to be used by women who were negatively impacted by BV for their sexual health (p = 0.008).

conclusionsBV is associated with negative quality of life and the women most impacted are seeking alternative treatments such as probiotics (Lactobacillus) and boric acid. There needs to be improvements in BV treatment that include alternative therapy options that have demonstrated efficacy with standardized composition, formulation and dosage.

Indexed as

ProbioticsVaginosis, BacterialAdolescentAdultBoric AcidsCross-Sectional StudiesFemaleHumansLactobacillusQuality of LifeVaginaYoung Adultboric acidBoric AcidsAlternative therapiesBacterial vaginosisBoric acidLactobacillusRecurrent bacterial vaginosis

Identifiers

PMID36934289
PMCPMC10024842
OpenAlexW4327814751

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read90
identifiers read2
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.