Evidence map›Paper›PMID 36934109›Full record

ArticleScientific reports2023

Using disproportionality analysis to explore the association between periostitis and triazole antifungals in the FDA Adverse Event Reporting System Database.

Hailong Li, Miao Zhang, Xuefeng Jiao, Yu Zhu, Yan Liu, Linan Zeng, Huiqing Wang, Lei Zhang, Wei Zhang, Lingli Zhang

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In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Observational
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hailong LiDepartment of Pharmacy, West China Second University Hospital, Sichuan University, Chengdu, China.
Miao ZhangDepartment of Pharmacy, West China Second University Hospital, Sichuan University, Chengdu, China.
Xuefeng JiaoDepartment of Pharmacy, West China Second University Hospital, Sichuan University, Chengdu, China.
Yu ZhuKey Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, Sichuan University, Chengdu, China.
Yan LiuDepartment of Pharmacy, West China Second University Hospital, Sichuan University, Chengdu, China.
Linan ZengDepartment of Pharmacy, West China Second University Hospital, Sichuan University, Chengdu, China.
Huiqing WangKey Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, Sichuan University, Chengdu, China.
Lei ZhangCollege of Computer Science, Sichuan University, Chengdu, China.
Wei ZhangWest China Biomedical Big Data Center, West China Hospital, Sichuan University, Chengdu, China. zhangwei@wchscu.cn.
Lingli ZhangDepartment of Pharmacy, West China Second University Hospital, Sichuan University, Chengdu, China. zhanglingli@scu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Though triazole antifungals are the first choice for preventing and treating invasive fungal infections, periostitis caused by voriconazole has been described in emerging case reports; however, no studies exist on this association in real-world clinical settings. Our study aimed to identify the association between periostitis and triazole antifungals by analyzing data from the FDA Adverse Event Reporting System (FAERS). We extracted and analyzed reports on the association between periostitis and triazole antifungals in FAERS from the first quarter of 2004 to the second quarter of 2022 using OpenVigil 2.1. Disproportionality analysis was performed to evaluate the association between periostitis and triazole antifungals, and chi-squared (χ

Indexed as

Antifungal AgentsPeriostitisAdverse Drug Reaction Reporting SystemsBayes TheoremHumansProspective StudiesUnited StatesUnited States Food and Drug AdministrationVoriconazoleAntifungal AgentsVoriconazole

Identifiers

PMID36934109
PMCPMC10024698

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.