Evidence map›Paper›PMID 36934108›Full record

ArticleNature communications2023

Spatial transcriptomics using multiplexed deterministic barcoding in tissue.

Johannes Wirth, Nina Huber, Kelvin Yin, Sophie Brood, Simon Chang, Celia P Martinez-Jimenez, Matthias Meier

Open access · goldFull text read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 37 citations in OpenAlex.

  1. Insights Into Spatial Transcriptomics: Exploring Recent Technical Developments and Their Diverse Applications.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  2. Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
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  9. A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Johannes WirthHelmholtz Pioneer Campus, Helmholtz Munich, Munich, Germany.ORCID 0000-0002-2216-3332
Nina HuberHelmholtz Pioneer Campus, Helmholtz Munich, Munich, Germany.
Kelvin YinHelmholtz Pioneer Campus, Helmholtz Munich, Munich, Germany.
Sophie BroodHelmholtz Pioneer Campus, Helmholtz Munich, Munich, Germany.
Simon ChangHelmholtz Pioneer Campus, Helmholtz Munich, Munich, Germany.
Celia P Martinez-JimenezHelmholtz Pioneer Campus, Helmholtz Munich, Munich, Germany. celia.martinez@helmholtz-muenchen.de.ORCID 0000-0002-9534-6201
Matthias MeierHelmholtz Pioneer Campus, Helmholtz Munich, Munich, Germany. matthias.meier@helmholtz-muenchen.de.ORCID 0000-0001-9455-4538
Helmholtz Zentrum München · DEHelmholtz Association of German Research Centres · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spatially resolved transcriptomics of tissue sections enables advances in fundamental and applied biomedical research. Here, we present Multiplexed Deterministic Barcoding in Tissue (xDBiT) to acquire spatially resolved transcriptomes of nine tissue sections in parallel. New microfluidic chips were developed to spatially encode mRNAs over a total tissue area of 1.17 cm

Indexed as

Gene Expression ProfilingTranscriptomeAnimalsMiceRNA, MessengerRNA, Messenger

Identifiers

PMID36934108
PMCPMC10024691
OpenAlexW4327857954

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read107
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.