ArticleNature communications2023
Aberrant survival of hippocampal Cajal-Retzius cells leads to memory deficits, gamma rhythmopathies and susceptibility to seizures in adult mice.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
- Network integration of neocortical Cajal-Retzius neurons shapes early cortical dynamics and contributes to their transient nature.Cell communication and signaling : CCS · 2026Article
- Partial Deletion ofeNeuro · 2026Article
- Capicua regulates the survival of Cajal-Retzius cells in the postnatal hippocampus.Cell death & disease · 2025Article
- Differences in Cajal-Retzius Cell Density and Postnatal Persistence Across Cortical Areas Revealed by a Novel Intersectional Genetic Labeling Approach.The Journal of comparative neurology · 2025Article
- Estrogenic regulation of hippocampal inhibitory system across lifespan.Journal of neuroendocrinology · 2025Review
- Decreasing β-Catenin Leads to Altered Endothelial Morphology, Increased Barrier Permeability and Cognitive Impairment During Chronic Methamphetamine Exposure.International journal of molecular sciences · 2025Article
- GABAergic integration of transient and persistent neurons in the developing mouse somatosensory cortex.Frontiers in cellular neuroscience · 2025Article
- GPATCH11 variants cause mis-splicing and early-onset retinal dystrophy with neurological impairment.Nature communications · 2024Article
- Rohon-beard neurons do not succumb to programmed cell death during zebrafish development.Developmental biology · 2024Article
- Postnatal persistence of hippocampal Cajal-Retzius cells has a crucial role in the establishment of the hippocampal circuit.Development (Cambridge, England) · 2024Article
- A Versatile Strategy for Genetic Manipulation of Cajal-Retzius Cells in the Adult Mouse Hippocampus.eNeuro · 2023Article
- Calcium Signaling during Cortical Apical Dendrite Initiation: A Role for Cajal-Retzius Neurons.International journal of molecular sciences · 2023Article
- Different activity patterns control various stages of Reelin synthesis in the developing neocortex.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Activation of the PI3K/AKT/mTOR Pathway in Cajal-Retzius Cells Leads to Their Survival and Increases Susceptibility to Kainate-Induced Seizures.International journal of molecular sciences · 2023Article
Corrections and comments
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Authors and funding
21 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cajal-Retzius cells (CRs) are transient neurons, disappearing almost completely in the postnatal neocortex by programmed cell death (PCD), with a percentage surviving up to adulthood in the hippocampus. Here, we evaluate CR's role in the establishment of adult neuronal and cognitive function using a mouse model preventing Bax-dependent PCD. CRs abnormal survival resulted in impairment of hippocampus-dependent memory, associated in vivo with attenuated theta oscillations and enhanced gamma activity in the dorsal CA1. At the cellular level, we observed transient changes in the number of NPY
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