ArticleNPJ vaccines2023
SARS-CoV-2 spike-ferritin-nanoparticle adjuvanted with ALFQ induces long-lived plasma cells and cross-neutralizing antibodies.
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Article in NPJ vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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0cells of the map it votes in
18citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 19 citations in OpenAlex.
- SARS-CoV-2 recombinant spike ferritin nanoparticle vaccine adjuvanted with Army Liposome Formulation containing monophosphoryl lipid A and QS-21: a phase 1, randomised, double-blind, placebo-controlled, first-in-human clinical trial.The Lancet. Microbe · 2024Trial
- Article
- ALFQ adjuvanted HIV-1 envelope protein vaccination elicits durable functional antibody and cellular responses in nonhuman primates.NPJ vaccines · 2025Article
- HIV vaccine candidate ΔV1gp120 formulated in ALFQA adjuvant augments mucosal immunity in female macaques.Nature communications · 2025Article
- Review
- Review
- Mixed lipopeptide-based mucosal vaccine elicits a long-term bone marrow memory response that is potentially cross-reactive against a broad-spectrum of coronaviruses in mice.Frontiers in immunology · 2025Article
- Review
- SARS-CoV-2 ferritin nanoparticle vaccines produce hyperimmune equine sera with broad sarbecovirus activity.iScience · 2024Article
- Ferritin Vaccine Platform for Animal and Zoonotic Viruses.Vaccines · 2024Review
- Ferritin Nanoparticle Delivery of the E2 Protein of Classical Swine Fever Virus Completely Protects Pigs from Lethal Challenge.Vaccines · 2024Article
- A Self-Assembling Pfs230D1-Ferritin Nanoparticle Vaccine Has Potent and Durable Malaria Transmission-Reducing Activity.Vaccines · 2024Article
- Review
- In search of a pan-coronavirus vaccine: next-generation vaccine design and immune mechanisms.Cellular & molecular immunology · 2024Review
- Article
- Application and Method of Surface Plasmon Resonance Technology in the Preparation and Characterization of Biomedical Nanoparticle Materials.International journal of nanomedicine · 2024Review
- Development of semisynthetic saponin immunostimulants.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2024Review
- Article
Corrections and comments
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Authors and funding
28 authors at 4 institutions in 1 country.
Shikha ShrivastavaLaboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0001-6276-0791
Joshua M CarmenLaboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Zhongyan LuDepartment of Pediatrics, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Shraddha BasuLaboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Rajeshwer S SankhalaHenry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
Wei-Hung ChenHenry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-3724-9195
Phuong NguyenLaboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0001-9664-2232
William C ChangHenry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-4967-6426
Jocelyn KingViral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0003-3348-1632
Courtney CorbittViral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Sandra MayerViral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0002-5767-8870
Jessica S BoltonMalaria Biologics Branch, Walter Reed Army Institute of Research, Silver Spring, USA.
Alexander AndersonLaboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0002-0000-7734
Isabella SwaffordHenry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.ORCID http://orcid.org/0000-0001-8638-2772
Guillermo D TerriquezLaboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Hung V TrinhLaboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0001-8014-9291
Jiae KimLaboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0003-2900-1667
Ousman JobeLaboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Dominic Paquin-ProulxHenry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-1407-3414
Gary R MatyasLaboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0002-2074-2373
Gregory D GromowskiCenter for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Jeffrey R CurrierCenter for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Elke Bergmann-LeitnerCenter for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0002-8571-8956
Kayvon ModjarradCenter for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Nelson L MichaelCenter for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
M Gordon JoyceHenry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-6808-7232
Allison M W MalloyDepartment of Pediatrics, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-2962-0302
Mangala RaoLaboratory of Adjuvant and Antigen Research, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA. mrao@hivresearch.org.ORCID http://orcid.org/0000-0001-9553-4969
Walter Reed Army Institute of Research · USHenry M. Jackson Foundation · USUniformed Services University of the Health Sciences · USOak Ridge Associated Universities · US
Funding
Respiratory mucosal immune development in early life and the quest for protective local memory against respiratory syncytial virus.R01AI154619 · NIAID · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI MALLOY, ALLISON MARIE WAHL · 2020 to 2023
$1.4MNIAID NIH HHS HHSN272201400008CNIAID NIH HHS R01 AI154619
Abstract
This study demonstrates the impact of adjuvant on the development of T follicular helper (Tfh) and B cells, and their influence on antibody responses in mice vaccinated with SARS-CoV-2-spike-ferritin-nanoparticle (SpFN) adjuvanted with either Army Liposome Formulation containing QS-21 (SpFN + ALFQ) or Alhydrogel
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.