Evidence map›Paper›PMID 36933150›Full record

ArticleCancer causes & control : CCC2023

Alcohol intake and the risk of epithelial ovarian cancer.

Kevin L'Espérance, Anne Grundy, Michal Abrahamowicz, Jocelyne Arseneau, Lucy Gilbert, Walter H Gotlieb, Diane Provencher, Anita Koushik

Abstract read
PubMed Publisher
In one paragraph

Article in Cancer causes & control : CCC, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Kevin L'EspéranceUniversité de Montréal Hospital Research Centre (CRCHUM), Tour Saint-Antoine, 850 Rue Saint-Denis, 3e étage, Bureau S03.436, Montreal, QC, H2X 0A9, Canada.ORCID http://orcid.org/0000-0003-1429-0988
Anne GrundyUniversité de Montréal Hospital Research Centre (CRCHUM), Tour Saint-Antoine, 850 Rue Saint-Denis, 3e étage, Bureau S03.436, Montreal, QC, H2X 0A9, Canada.
Michal AbrahamowiczDepartment of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada.
Jocelyne ArseneauDepartment of Pathology, McGill University Health Centre, Montreal, QC, Canada.
Lucy GilbertDivision of Gynecologic Oncology, McGill University Health Centre, Montreal, QC, Canada.
Walter H GotliebGynecologic Oncology and Colposcopy, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, QC, Canada.
Diane ProvencherUniversité de Montréal Hospital Research Centre (CRCHUM), Tour Saint-Antoine, 850 Rue Saint-Denis, 3e étage, Bureau S03.436, Montreal, QC, H2X 0A9, Canada.
Anita KoushikUniversité de Montréal Hospital Research Centre (CRCHUM), Tour Saint-Antoine, 850 Rue Saint-Denis, 3e étage, Bureau S03.436, Montreal, QC, H2X 0A9, Canada. anita.koushik@umontreal.ca.ORCID http://orcid.org/0000-0001-5304-7660
Université de Montréal · CAMcGill University Health Centre · CACentre Hospitalier de l’Université de Montréal · CAJewish General Hospital · CAMcGill University · CA

Funding

Canadian Cancer Society 700485Cancer Research Society 16264
6 · The paper itself

Abstract

purposeTo investigate the association between alcohol intake over the lifetime and the risk of overall, borderline, and invasive ovarian cancer.

methodsIn a population-based case-control study of 495 cases and 902 controls, conducted in Montreal, Canada, average alcohol intake over the lifetime and during specific age periods were computed from a detailed assessment of the intake of beer, red wine, white wine and spirits. Multivariable logistic regression was used to estimate odds ratios (ORs) with 95% confidence intervals (CIs) for the association between alcohol intake and ovarian cancer risk.

resultsFor each one drink/week increment in average alcohol intake over the lifetime, the adjusted OR (95% CI) was 1.06 (1.01-1.10) for ovarian cancer overall, 1.13 (1.06-1.20) for borderline ovarian cancers and 1.02 (0.97-1.08) for invasive ovarian cancers. This pattern of association was similarly observed for alcohol intake in early (15- < 25 years), mid (25- < 40 years) and late adulthood (≥ 40 years), as well as for the intake of specific alcohol beverages over the lifetime.

conclusionsOur results support the hypothesis that a higher alcohol intake modestly increases the risk of overall ovarian cancer, and more specifically, borderline tumours.

Indexed as

Alcohol DrinkingOvarian NeoplasmsAdultBeerCarcinoma, Ovarian EpithelialCase-Control StudiesFemaleHumansRisk FactorsAlcohol drinkingBeerCase–control studiesOvarian neoplasmsSpiritWine

Identifiers

PMID36933150
OpenAlexW4327811564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.