Evidence map›Paper›PMID 36933046›Full record

ArticleClinical oral investigations2023

Enhanced effect of a novel bioactive glass-ceramic for dental application.

Lin Qiu, Yu Lu, Haide Dong, Huan Zhang, Min Zhang, Quanfu Deng, Jinlin Song

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical oral investigations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Lin QiuDencare (Chongqing) Oral Care Co., Ltd, Chongqing, China. qiulin@dencare.com.cn.
Yu LuDencare (Chongqing) Oral Care Co., Ltd, Chongqing, China.
Haide DongDencare (Chongqing) Oral Care Co., Ltd, Chongqing, China.
Huan ZhangDencare (Chongqing) Oral Care Co., Ltd, Chongqing, China.
Min ZhangDencare (Chongqing) Oral Care Co., Ltd, Chongqing, China.
Quanfu DengDencare (Chongqing) Oral Care Co., Ltd, Chongqing, China. dengquanfu@dencare.com.cn.
Jinlin SongCollege of Stomatology, Chongqing Medical University, Chongqing, China. songjinlin@hospital.cqmu.edu.cn.
Chongqing Medical University · CNDenso (United States) · USStomatological Hospital of Chongqing Medical University · CN

Funding

2019 Chongqing Graduate Mentor Team Funding dstd201903
6 · The paper itself

Abstract

objectivesDental caries is the most common chronic disease in humans, caused by the acid produced by the microflora in the mouth that dissolves the enamel minerals. Bioactive glass (BAG) has been used in various clinical applications due to its unique bioactive properties, such as bone graft substitutes and dental restorative composites. In this study, we introduce a novel bioactive glass-ceramic (NBGC) prepared through a sol-gel process under a water-free condition. MATERIALS AND

methodsThe anti-demineralization and remineralization effects of NBGC were evaluated by comparing the measurements of bovine enamel surface morphology, surface roughness, surface micro-hardness, enamel elements, and mineral content before and after related treatments with a commercial BAG. The antibacterial effect was characterized by minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC).

resultsResults showed that NBGC had greater acid resistance and remineralization potential compared to commercial BAG. The fast formation of a hydroxy carbonate apatite (HCA) layer suggests efficient bioactivity. CLINICAL RELEVANCE: In addition to its antibacterial properties, NBGC shows promise as an ingredient in oral care products that can prevent demineralization and restore enamel.

Indexed as

Dental CariesAnimalsAnti-Bacterial AgentsCattleCeramicsDental EnamelHardnessHumansMineralsTooth RemineralizationAnti-Bacterial AgentsMineralsBioactiveDemineralizationDentalEnamelRemineralization

Identifiers

PMID36933046
OpenAlexW4327811554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.