Evidence map›Paper›PMID 36933041›Full record

ArticleAnnals of hematology2023

High TOX expression on CD8

Haiyue Niu, Li Yan, Liping Yang, Mengying Zhang, Mengyuan Liu, Jie Ren, Zonghong Shao, Rong Fu, Limin Xing, Huaquan Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of hematology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Aberrant Hematopoiesis and CD8Thoracic cancer · 2025
    Article
  3. Molecular landscape of CD8Annals of hematology · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Haiyue Niu *Department of Hematology, General Hospital, Tianjin Medical University, Tianjin, 300052, China.
Li Yan *Department of Hematology, General Hospital, Tianjin Medical University, Tianjin, 300052, China.
Liping Yang *Department of Hematology, General Hospital, Tianjin Medical University, Tianjin, 300052, China.
Mengying ZhangDepartment of Hematology, General Hospital, Tianjin Medical University, Tianjin, 300052, China.
Mengyuan LiuDepartment of Hematology, General Hospital, Tianjin Medical University, Tianjin, 300052, China.
Jie RenDepartment of Hematology, General Hospital, Tianjin Medical University, Tianjin, 300052, China.
Zonghong ShaoDepartment of Hematology, General Hospital, Tianjin Medical University, Tianjin, 300052, China.
Rong FuDepartment of Hematology, General Hospital, Tianjin Medical University, Tianjin, 300052, China.
Limin XingDepartment of Hematology, General Hospital, Tianjin Medical University, Tianjin, 300052, China.
Huaquan WangDepartment of Hematology, General Hospital, Tianjin Medical University, Tianjin, 300052, China. wanghuaquan@tmu.edu.cn.ORCID http://orcid.org/0000-0003-2402-2717
Tianjin Medical University General Hospital · CN

Funding

Tianjin Research Program of Application Foundation and Advanced Technology of China 18ZXDBSY00140
6 · The paper itself

Abstract

Thymocyte selection-associated high-mobility group box protein (TOX) is an important molecule regulating the development and exhaustion of T lymphocytes. Our aim is to investigate the role of TOX in the immune pathogenesis of pure red cell aplasia (PRCA). TOX expression of CD8

Indexed as

CD8-Positive T-LymphocytesRed-Cell Aplasia, PureGranzymesHigh Mobility Group ProteinsHumansPerforinT-Lymphocytes, RegulatoryGranzymesHigh Mobility Group ProteinsPerforinTOX protein, humanLAG3PD1Pure red cell aplasiaT lymphocyteTOX

Identifiers

PMID36933041
OpenAlexW4327811393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.