Evidence map›Paper›PMID 36932731›Full record

ArticleThe Journal of infectious diseases2023

Nationwide Hepatitis C Serosurvey and Progress Towards Hepatitis C Virus Elimination in the Country of Georgia, 2021.

Amiran Gamkrelidze, Shaun Shadaker, Maia Tsereteli, Maia Alkhazashvili, Nazibrola Chitadze, Irina Tskhomelidze, Lia Gvinjilia, Nino Khetsuriani, Senad Handanagic, Francisco Averhoff and 6 more

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  13. Prevalence of transfusion transmitted infections by mode of donation and remuneration status among blood donors in Georgia, 2018-2023.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2025
    Article
  14. Risk factors for HCV infection in Georgia: A case-control study.Journal of infection in developing countries · 2025
    Article
  15. Article
  16. Trends in new hepatitis C virus infections among repeat blood donors - Georgia, 2017-2023.Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Amiran GamkrelidzeNational Center for Disease Control and Public Health, Tbilisi, Georgia.
Shaun ShadakerDivision of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0002-5772-7046
Maia TsereteliNational Center for Disease Control and Public Health, Tbilisi, Georgia.
Maia AlkhazashviliNational Center for Disease Control and Public Health, Tbilisi, Georgia.
Nazibrola ChitadzeNational Center for Disease Control and Public Health, Tbilisi, Georgia.
Irina TskhomelidzeThe Task Force for Global Health, Tbilisi, Georgia.
Lia GvinjiliaEastern Europe and Central Asia Regional Office, Centers for Disease Control and Prevention, Tbilisi, Georgia.
Nino KhetsurianiGlobal Immunization Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Senad HandanagicDivision of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Francisco AverhoffAbbott Diagnostics, Abbott Park, IL, USA.
Gavin ClohertyAbbott Diagnostics, Abbott Park, IL, USA.
Giorgi ChakhunashviliNational Center for Disease Control and Public Health, Tbilisi, Georgia.
Jan DrobeniucDivision of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Paata ImnadzeNational Center for Disease Control and Public Health, Tbilisi, Georgia.
Khatuna ZakhashviliNational Center for Disease Control and Public Health, Tbilisi, Georgia.
Paige A ArmstrongDivision of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Funding

CDC HHSIntramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundThe country of Georgia initiated its hepatitis C virus (HCV) elimination program in 2015, at which point a serosurvey showed the adult prevalence of HCV antibody (anti-HCV) and HCV RNA to be 7.7% and 5.4%, respectively. This analysis reports hepatitis C results of a follow-up serosurvey conducted in 2021, and progress towards elimination.

methodsThe serosurvey used a stratified, multistage cluster design with systematic sampling to include adults and children (aged 5-17 years) providing consent (or assent with parental consent). Blood samples were tested for anti-HCV and if positive, HCV RNA. Weighted proportions and 95% confidence intervals (CI) were compared with 2015 age-adjusted estimates.

resultsOverall, 7237 adults and 1473 children were surveyed. Among adults, the prevalence of anti-HCV was 6.8% (95% CI, 5.9-7.7). The HCV RNA prevalence was 1.8% (95% CI, 1.3-2.4), representing a 67% reduction since 2015. HCV RNA prevalence decreased among those reporting risk factors of ever injecting drugs (51.1% to 17.8%), and ever receiving a blood transfusion (13.1% to 3.8%; both P < .001). No children tested positive for anti-HCV or HCV RNA.

conclusionsThese results demonstrate substantial progress made in Georgia since 2015. These findings can inform strategies to meet HCV elimination targets.

Indexed as

HepacivirusHepatitis CAdultGeorgiaHumansPrevalenceRisk FactorsRNARNAeliminationGeorgiahepatitis Cprevalenceserosurvey

Identifiers

PMID36932731
PMCPMC10506179

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.