ReviewMolecular plant pathology2023
The function of plant PR1 and other members of the CAP protein superfamily in plant-pathogen interactions.
Review in Molecular plant pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
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Who cites it
70 citing papers in PubMed, 132 citations in OpenAlex.
- SOBIR1 integrates pathogen recognition and hormonal metabolism in Nicotiana tabacum.Plant physiology · 2026Article
- A PR1-Like Protein Stabilizes a Barwin-Like Protein to Enhance Wheat Resistance to Leaf Rust.Plant, cell & environment · 2026Article
- Design, synthesis, and antiviral activity of novel piperidine-containing pyrazoleamide derivatives.Pest management science · 2026Article
- Comprehensive Identification and Integrated Analysis of theLife (Basel, Switzerland) · 2026Article
- Genome-Wide Characterization of CAPE-ProducingPlants (Basel, Switzerland) · 2026Article
- Early seed priming with closely relatedHorticulture research · 2026Article
- Comparative transcriptome analysis reveals the responses of sweetpotato to continuous cropping stress.BMC plant biology · 2026Article
- Article
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- Biocontrol of strawberry powdery mildew by Bacillus altitudinis DXHS: mechanistic insights from transcriptome analysis.BMC plant biology · 2026Article
- Dissecting multi-rust resistance in wheat through genome-wide association study, haplotype analysis, and marker validation.The plant genome · 2026Article
- Genome-Wide Identification and Expression Analysis of Pathogenesis-Related Protein 1 in Sweet Potato and Its Two Relatives.Food science & nutrition · 2026Article
- TaSPX3 Enhances Wheat Resistance to Leaf Rust by Antagonising TaDi19-Mediated Repression of Pathogenesis-Related Genes.Plant biotechnology journal · 2026Article
- Exploring Pinus nigra's induced defense arsenal against Diplodia sapinea through gene and metabolic pathway analysis.BMC genomics · 2026Article
- HIPPs of all trades: insights from pathogens on the function of HMA proteins at plasmodesmata.Journal of experimental botany · 2026Review
- A Core Effector MoPce1 Is Required for the Pathogenicity of Magnaporthe oryzae by Modulating Catalase-Mediated HMolecular plant pathology · 2026Article
- The Arabidopsis deNADding Enzyme DXO1 Modulates the Plant Immunity Response.Plant, cell & environment · 2026Article
- Selected cell wall-associated components in plant defense responses against microbial pathogens.Frontiers in plant science · 2026Review
- Agro-physiological responses and molecular docking evaluation of some essential oils and ascorbic acid as eco-friendly inhibitors of powdery mildew in cucumber plants.Frontiers in plant science · 2026Article
- Evaluation of antifungal activity ofFrontiers in plant science · 2026Article
10 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pathogenesis-related (PR) proteins of plants have originally been identified as proteins that are strongly induced upon biotic and abiotic stress. These proteins fall into 17 distinct classes (PR1-PR17). The mode of action of most of these PR proteins has been well characterized, except for PR1, which belongs to a widespread superfamily of proteins that share a common CAP domain. Proteins of this family are not only expressed in plants but also in humans and in many different pathogens, including phytopathogenic nematodes and fungi. These proteins are associated with a diverse range of physiological functions. However, their precise mode of action has remained elusive. The importance of these proteins in immune defence is illustrated by the fact that PR1 overexpression in plants results in increased resistance against pathogens. However, PR1-like CAP proteins are also produced by pathogens and deletion of these genes results in reduced virulence, suggesting that CAP proteins can exert both defensive and offensive functions. Recent progress has revealed that plant PR1 is proteolytically cleaved to release a C-terminal CAPE1 peptide, which is sufficient to activate an immune response. The release of this signalling peptide is blocked by pathogenic effectors to evade immune defence. Moreover, plant PR1 forms complexes with other PR family members, including PR5, also known as thaumatin, and PR14, a lipid transfer protein, to enhance the host's immune response. Here, we discuss possible functions of PR1 proteins and their interactors, particularly in light of the fact that these proteins can bind lipids, which have important immune signalling functions.
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