ArticleMedical science monitor : international medical journal of experimental and clinical research2023
Effect of Polylactic Acid Membrane on Guided Bone Regeneration in Anterior Maxillary Implantation.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 11 citations in OpenAlex.
- Comparative Analysis of Gelatin/Polylactic Acid and Commercial PLA Membranes for Guided Bone Regeneration: A Randomized Clinical Trial.Medical science monitor : international medical journal of experimental and clinical research · 2025Trial
- An Update Regarding the Use of Contemporary Dental Materials in Periodontal Regeneration.Materials (Basel, Switzerland) · 2025Review
- Advances in Synthetic Polymer Membranes for Guided Bone Regeneration in Dental Implants: A Scoping Review.Journal of functional biomaterials · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND This study evaluated the clinical efficacy of polylactic acid (PLA) membranes in guiding bone regeneration in anterior maxillary implants. MATERIAL AND METHODS Forty-eight participants with maxillary anterior tooth loss requiring implantation with guided bone regeneration were recruited and randomly divided into 2 groups (n=24): the PLA membrane (experimental) and the Bio-Gide membrane (control) group. Wound healing was observed at 1 week and 1 month postoperatively. Cone beam CT was performed immediately and at 6 and 36 months postoperatively. Soft-tissue parameters were measured at 18 and 36 months postoperatively. Implant stability quotient (ISQ) and patient satisfaction were separately evaluated at 6 and 18 months after the operation. The independent sample t test and chi-square test were preformed to analyze quantitative and descriptive statistics, respectively. RESULTS No implants were lost and there were no statistically significant differences in ISQ between the 2 groups. The labial bone plates in the experimental group exhibited a non-significantly greater extent of absorption than did the control group at 6 and 18 months postoperatively. Soft-tissue parameters did not reveal inferior results for the experimental group. Patients in both groups were satisfied. CONCLUSIONS PLA membranes are comparable to Bio-Gide in terms of the effectiveness and safety and can be used as a barrier membrane to guide bone regeneration in clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.