Evidence map›Paper›PMID 36932331›Full record

ArticleThe journal of headache and pain2023

A novel score to estimate thrombus burden and predict intracranial hypertension in cerebral venous sinus thrombosis.

Zhongao Wang, Chaitu Dandu, Yibing Guo, Meini Gao, Duo Lan, Liqun Pan, Da Zhou, Yuchuan Ding, Xunming Ji, Ran Meng

Open access · goldFull text read
In one paragraph

Article in The journal of headache and pain, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Zhongao WangDepartment of Neurology, National Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.ORCID http://orcid.org/0000-0002-4234-7593
Chaitu DanduDepartment of Neurosurgery, Wayne State University School of Medicine, Detroit, Michigan, 48201, USA.
Yibing GuoDepartment of Neurology, National Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Meini GaoDepartment of Neurology, National Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Duo LanDepartment of Neurology, National Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Liqun PanDepartment of Neurology, National Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Da ZhouDepartment of Neurology, National Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Yuchuan DingDepartment of Neurosurgery, Wayne State University School of Medicine, Detroit, Michigan, 48201, USA.
Xunming JiDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.ORCID http://orcid.org/0000-0003-0293-2744
Ran MengDepartment of Neurology, National Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China. victor65@126.com.ORCID http://orcid.org/0000-0003-1190-4710
Capital Medical University · CNWayne State University · US

Funding

National Natural Science Foundation of China 82101390National Natural Science Foundation of China 82171297Natural Science Foundation of Beijing Municipality 7212047
6 · The paper itself

Abstract

backgroundCurrent methods to evaluate the severity of cerebral venous sinus thrombosis (CVST) lack patient-specific indexes. Herein, a novel scoring method was investigated to estimate the thrombus burden and the intracranial pressure (ICP) of CVST.

methodsIn this retrospective study from January 2019 through December 2021, we consecutively enrolled patients with a first-time confirmed diagnosis of CVST by contrast-enhanced magnetic resonance venography (CE-MRV) or computed tomography venography (CTV). In these patients, a comprehensive CVST-Score was established using magnetic resonance black-blood thrombus imaging (MRBTI) to estimate the thrombus burden semi-quantitatively. The relationship between CVST-Score and ICP was explored to assess the potential of using the CVST-score to evaluate ICP noninvasively and dynamically.

resultsA total of 87 patients were included in the final analysis. The CVST-Scores in different ICP subgroups were as follows: 4.29±2.87 in ICP<250mmH

conclusionsA simple and noninvasive CVST-Score can rapidly estimate the thrombus burden and predict the severity of intracranial hypertension in patients with CVST. The CVST-Score can aid in evaluating therapeutic responses and avoiding unnecessary invasive procedures at long-term follow-up.

Indexed as

Intracranial HypertensionSinus Thrombosis, IntracranialThrombosisHumansMagnetic Resonance ImagingRetrospective StudiesCerebral venous sinus thrombosisIntracranial pressureMagnetic resonance black-blood thrombus imagingScoring methodThrombus burden

Identifiers

PMID36932331
PMCPMC10022088
OpenAlexW4327738975

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.