ReviewJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology2023
Lineages to circuits: the developmental and evolutionary architecture of information channels into the central complex.
Review in Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 35 citations in OpenAlex.
- Article
- Article
- Temporal gating of sex-specific apoptosis shapes the sexually dimorphic brain.Cell genomics · 2026Article
- Unexpected Evolutionary Divergence of Tachykinin-Positive Neurons Innervating the Central Complex in Hexapods.The Journal of comparative neurology · 2026Article
- Hormonal control of postmitotic neuronal identity.bioRxiv : the preprint server for biology · 2026Article
- Brain morphology in the peracarid crustacean Neomysis integer (Leach, 1814) with an emphasis on sexual dimorphism of the olfactory pathway.Cell and tissue research · 2025Article
- Article
- Neuronal Circuit Evolution: From Development to Structure and Adaptive Significance.Cold Spring Harbor perspectives in biology · 2025Review
- Transcriptional complexity in the insect central complex: single nuclei RNA-sequencing of adult brain neurons derived from type 2 neuroblasts.bioRxiv : the preprint server for biology · 2025Article
- Neuroarchitecture of the Central Complex in the Madeira Cockroach Rhyparobia maderae: Tangential Neurons.The Journal of comparative neurology · 2024Article
- Stem cell-specific ecdysone signaling regulates the development of dorsal fan-shaped body neurons and sleep homeostasis.Current biology : CB · 2024Article
- Neural circuits for goal-directed navigation across species.Trends in neurosciences · 2024Review
- From bristle to brain: embryonic development of topographic projections from basiconic sensilla in the antennal nervous system of the locust Schistocerca gregaria.Development genes and evolution · 2024Article
- Article
- The conserved RNA-binding protein Imp is required for the specification and function of olfactory navigation circuitry in Drosophila.Current biology : CB · 2024Article
- Stem cell-specific ecdysone signaling regulates the development and function of abioRxiv : the preprint server for biology · 2023Article
- Unraveling the neural basis of spatial orientation in arthropods.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2023Article
- The RNA-binding protein, Imp specifies olfactory navigation circuitry and behavior inbioRxiv : the preprint server for biology · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
The representation and integration of internal and external cues is crucial for any organism to execute appropriate behaviors. In insects, a highly conserved region of the brain, the central complex (CX), functions in the representation of spatial information and behavioral states, as well as the transformation of this information into desired navigational commands. How does this relatively invariant structure enable the incorporation of information from the diversity of anatomical, behavioral, and ecological niches occupied by insects? Here, we examine the input channels to the CX in the context of their development and evolution. Insect brains develop from ~ 100 neuroblasts per hemisphere that divide systematically to form "lineages" of sister neurons, that project to their target neuropils along anatomically characteristic tracts. Overlaying this developmental tract information onto the recently generated Drosophila "hemibrain" connectome and integrating this information with the anatomical and physiological recording of neurons in other species, we observe neuropil and lineage-specific innervation, connectivity, and activity profiles in CX input channels. We posit that the proliferative potential of neuroblasts and the lineage-based architecture of information channels enable the modification of neural networks across existing, novel, and deprecated modalities in a species-specific manner, thus forming the substrate for the evolution and diversification of insect navigational circuits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.