Evidence map›Paper›PMID 36931487›Full record

ArticleExperimental eye research2023

The accumulated oxygen deficit as an indicator of the ischemic retinal insult.

Norman P Blair, Nathanael Matei, Sophie Leahy, Mansour Rahimi, Mahnaz Shahidi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental eye research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Norman P BlairDepartment of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 1855 West Taylor Street, Chicago, IL 60612, USA. Electronic address: npblair@uic.edu.
Nathanael MateiDepartment of Ophthalmology, University of Southern California, 1450 San Pablo St, Suite 4700, Los Angeles, CA 9003, USA. Electronic address: nmate001@ucr.edu.
Sophie LeahyDepartment of Ophthalmology, University of Southern California, 1450 San Pablo St, Suite 4700, Los Angeles, CA 9003, USA. Electronic address: sleahy@usc.edu.
Mansour RahimiDepartment of Ophthalmology, University of Southern California, 1450 San Pablo St, Suite 4700, Los Angeles, CA 9003, USA. Electronic address: mansourr@usc.edu.
Mahnaz ShahidiDepartment of Ophthalmology, University of Southern California, 1450 San Pablo St, Suite 4700, Los Angeles, CA 9003, USA. Electronic address: mshahidi@usc.edu.
University of Southern California · USUniversity of Illinois Chicago · US

Funding

Ophthalmic Therapeutics Engineering CoreP30EY029220 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Mahnaz Shahidi · 2018 to 2026
$6.5M
Noninvasive Imaging of Chorioretinal Oxygen TensionR01EY017918 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SHAHIDI, MAHNAZ · 2007 to 2022
$6.2M
NEI NIH HHS P30 EY029220NEI NIH HHS R01 EY017918
6 · The paper itself

Abstract

We here attempt to improve quantification of the ischemic retinal insult, that is, what is imposed on the retinal tissue by ischemia, especially in experimental models of ischemia. The ischemic retinal insult initiates the ischemic retinal injury (or outcome). Accordingly, it is reasonable to assume that the better the quantification of the insult, the better the correlation with, and thereby estimation of, the injury. The insult seldom has been quantified in terms of the relevant physiological factors, especially in connection with the rate of oxygen delivery (DO

Indexed as

OxygenRetinal DiseasesAnimalsIschemiaRatsRetinaRetinal VesselsOxygenImagingRetinal blood flowRetinal ischemiaRetinal oxygen deliveryRetinal oxygen metabolism

Identifiers

PMID36931487
PMCPMC10133208
OpenAlexW4324365327

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.