Evidence map›Paper›PMID 36931331›Full record

ArticleNeuroImage2023

Test-retest reliability of 3D velocity-selective arterial spin labeling for detecting normal variations of cerebral blood flow.

Feng Xu, Dapeng Liu, Dan Zhu, Argye E Hillis, Arnold Bakker, Anja Soldan, Marilyn S Albert, Doris D M Lin, Qin Qin

Open access · goldAbstract read
In one paragraph

Article in NeuroImage, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Feng XuThe Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University, Baltimore, MD 21205, USA; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD 21205, USA. Electronic address: feng.xu@jhu.edu.
Dapeng LiuThe Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University, Baltimore, MD 21205, USA; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD 21205, USA.
Dan ZhuThe Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University, Baltimore, MD 21205, USA; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD 21205, USA.
Argye E HillisDepartment of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.
Arnold BakkerDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD 21287, USA.
Anja SoldanDepartment of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.
Marilyn S AlbertDepartment of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.
Doris D M LinThe Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University, Baltimore, MD 21205, USA.
Qin QinThe Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University, Baltimore, MD 21205, USA; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD 21205, USA.
Johns Hopkins University · USKennedy Krieger Institute · US

Funding

Research Education ComponentP30AG066507 · NIA · JOHNS HOPKINS UNIVERSITY · PI Corinne Pettigrew · 2020 to 2026
$29.3M
Sleep and Circadian Dysfunction, Brain and Neurobehavioral Development in AutismP50HD103538 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Stewart H Mostofsky · 2020 to 2026
$9.9M
TRD 4: Platforms for multi-modal and multi-scale imaging dataP41EB031771 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Hanzhang Lu, Peter CM Van Zijl · 2021 to 2026
$9.9M
Non-Contrast-Enhanced Velocity-Selective MR Angiography at 3T for Cerebrovascular DiseasesR01HL138182 · NHLBI · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI QIN, QIN · 2018 to 2022
$2.0M
Velocity-Selective Arterial Spin Labeling based Perfusion Mapping for Cerebrovascular DiseasesR01HL144751 · NHLBI · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI QIN, QIN · 2019 to 2022
$1.7M
NHLBI NIH HHS R01 HL138182NHLBI NIH HHS R01 HL144751NIA NIH HHS P30 AG066507NIBIB NIH HHS P41 EB031771NICHD NIH HHS P50 HD103538
6 · The paper itself

Abstract

Velocity-selective inversion (VSI) based velocity-selective arterial spin labeling (VSASL) has been developed to measure cerebral blood flow (CBF) with low susceptibility to the prolonged arterial transit time and high sensitivity to brain perfusion signal. The purpose of this magnetic resonance imaging study is to evaluate the test-retest reliability of a VSI-prepared 3D VSASL protocol with whole-brain coverage to detect baseline CBF variations among cognitively normal participants in different brain regions. Coefficients of variation (CoV) of both absolute and relative CBF across scans or sessions, subjects, and gray matter regions were calculated, and corresponding intraclass correlation coefficients (ICC) were computed. The higher between-subject CoV of absolute CBF (13.4 ± 2.0%) over within-subject CoV (within-session: 3.8 ± 1.1%; between-session: 4.9 ± 0.9%) yielded moderate to excellent ICC (within-session: 0.88±0.08; between-session: 0.77±0.14) to detect normal variations of individual CBF. The higher between-region CoV of relative CBF (11.4 ± 3.0%) over within-region CoV (within-session: 2.3 ± 0.9%; between-session: 3.3 ± 1.0%) yielded excellent ICC (within-session: 0.92±0.06; between-session: 0.85±0.12) to detect normal variations of regional CBF. Age, blood pressure, end-tidal CO

Indexed as

ArteriesMagnetic Resonance ImagingCerebrovascular CirculationHumansReproducibility of ResultsSpin LabelsSpin LabelsBetween-subject variationCerebral blood flowCoefficients of variationIntraclass correlation coefficientsTest-retest reliabilityVelocity selective arterial spin labeling

Identifiers

PMID36931331
PMCPMC10150252
OpenAlexW4327601927

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.