ArticleJournal of anatomy1986
Ultrastructural alterations in glycosaminoglycans of dog femoral condylar cartilage after surgical division of an anterior cruciate ligament: a study with cupromeronic blue in a critical electrolyte concentration technique.
Article in Journal of anatomy, 1986. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 12 citations in OpenAlex.
- Articular cartilage of the rabbit knee after synovectomy: a scanning electron microscopy study.Journal of anatomy · 1998Article
- Development of osteoarthritic lesions in mice by "metabolic" and "mechanical" alterations in the knee joints.The American journal of pathology · 1989Article
- Differential response to compressive loads of zones of canine hyaline articular cartilage: micromechanical, light and electron microscopic studies.Annals of the rheumatic diseases · 1988Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cationic dye, cupromeronic blue, has been used in a critical electrolyte concentration technique to analyse the ultrastructural changes in cartilage matrix glycosaminoglycans which occur in the dog anterior cruciate ligament division model of osteoarthrosis. Amorphous material appearing at the articular surface of cartilage from the stifle joints of animals subjected to open surgical division of the anterior cruciate ligament has been shown not to comprise glycosaminoglycan. The nature of this material is unknown, but it appears to replace the surface lamina of normal cartilage. It may therefore affect the mechanical properties of the superficial cartilage. The pericellular matrix around single chondrocytes or separating pairs of chondrocytes becomes enriched with sulphated glycosaminoglycan as a response to ligament section. This material is thought to be newly synthesised and secreted and reflects the increased cellular activity resulting from surgically induced canine joint disease.
Indexed as
Identifiers
3693089PMC1261604W2397096668What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.