Evidence map›Paper›PMID 36930389›Full record

ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2023

Concomitant diagnosis of multiple sclerosis and human immunodeficiency virus (HIV) infection: case report and the review of literature.

Assunta Trinchillo, Antonio Luca Spiezia, Antonio Carotenuto, Enrico Tedeschi, Giuseppe Servillo, Carmine Iacovazzo, Francesco Borrelli, Giovanni Di Filippo, Vincenzo Brescia Morra, Roberta Lanzillo

Erratum issuedAbstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Assunta TrinchilloDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, "Federico II" University, Naples, Italy. assuntatrinchillo94@gmail.com.ORCID http://orcid.org/0000-0002-9413-3394
Antonio Luca SpieziaDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, "Federico II" University, Naples, Italy.
Antonio CarotenutoDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, "Federico II" University, Naples, Italy.
Enrico TedeschiDepartment of Advanced Biomedical Sciences, "Federico II" University, Naples, Italy.
Giuseppe ServilloDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, "Federico II" University, Naples, Italy.
Carmine IacovazzoDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, "Federico II" University, Naples, Italy.
Francesco BorrelliInfectious Diseases Unit, "Federico II" University, Naples, Italy.
Giovanni Di FilippoInfectious Diseases Unit, "Federico II" University, Naples, Italy.
Vincenzo Brescia MorraDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, "Federico II" University, Naples, Italy.
Roberta LanzilloDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, "Federico II" University, Naples, Italy.
Federico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo date, few cases of multiple sclerosis (MS) patients with concomitant Human Immunodeficiency Virus (HIV) infection have been described. However, none of the previously described cases has been treated with Natalizumab, probably due to the increasing risk of progressive multifocal leukoencephalopathy (PML). CASE: We report the case of a patient concomitantly diagnosed for HIV infection and MS treated with combined antiretroviral therapy (cART) and Natalizumab for 19 months, without clinical or radiological MS activity.

conclusionsOur case might suggest considering Natalizumab in patients with concomitant HIV infection, especially for those with significant disease activity requiring a high efficacy disease modifying treatment.

Indexed as

HIV InfectionsLeukoencephalopathy, Progressive MultifocalMultiple SclerosisAntibodies, Monoclonal, HumanizedHIVHumansImmunologic FactorsNatalizumabAntibodies, Monoclonal, HumanizedImmunologic FactorsNatalizumabHIVMultiple sclerosisNatalizumab

Identifiers

PMID36930389
OpenAlexW4327683097

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.