Evidence map›Paper›PMID 36930272›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2023

Same-day versus staged revascularization of bilateral moyamoya arteriopathy in pediatric patients.

Risheng Xu, Michael E Xie, Jennifer Kim, Ruchita Kothari, Lisa R Sun, Eric M Jackson, Rafael J Tamargo, Judy Huang, Edward S Ahn, Alan R Cohen

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed, 0 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Risheng XuDepartment of Neurosurgery, Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD, 21287, USA.
Michael E XieDepartment of Neurosurgery, Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD, 21287, USA.
Jennifer KimDepartment of Neurosurgery, Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD, 21287, USA.
Ruchita KothariDepartment of Neurosurgery, Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD, 21287, USA.
Lisa R SunDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Eric M JacksonDepartment of Neurosurgery, Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD, 21287, USA.
Rafael J TamargoDepartment of Neurosurgery, Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD, 21287, USA.
Judy HuangDepartment of Neurosurgery, Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD, 21287, USA.
Edward S AhnDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA.
Alan R CohenDepartment of Neurosurgery, Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD, 21287, USA. alan.cohen@jhmi.edu.
Johns Hopkins Medicine · USJohns Hopkins University · USMayo Clinic · US

Funding

Medical Scientist Training ProgramT32GM136577 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ANDREA L COX · 2020 to 2026
$13.4M
NIGMS NIH HHS T32 GM136577
6 · The paper itself

Abstract

purposeTo compare the outcomes of conducting left and right hemisphere surgical revascularization on the same day versus different days for bilateral pediatric moyamoya arteriopathy patients.

methodsWe retrospectively analyzed mortality, stroke, and transient neurologic event (TNE) rates in North American bilateral pediatric moyamoya arteriopathy patients who underwent bilateral cerebral revascularization.

resultsA total of 38 pediatric (≤ 18 years old) patients at our institution underwent bilateral cerebral revascularization for moyamoya arteriopathy. Of these patients, 24 (63.2%) had both operations on the same day and 14 (36.8%) had the two operations on different days. The average length of stay for patients who underwent same-day bilateral revascularization was 6.9 ± 2.0 days and the average length of stay for each operation for patients who underwent staged bilateral revascularization was 4.5 ± 1.4 days, p = 0.001. While there were 7 (14.6%) postoperative strokes in patients who had both hemispheres revascularized on the same day, 0 (0%) strokes occurred in hemispheres after they had been operated on in the staged cohort, p = 0.042. Additionally, the postoperative stroke-free survival time in the ipsilateral hemisphere and TNE-free survival time were significantly longer in patients in the staged revascularization cohort.

conclusionSame-day bilateral revascularization was associated with longer length of stay per operation, higher rate of ipsilateral stroke, and shorter postoperative TNE-free and stroke-free survival time in the revascularized hemisphere.

Indexed as

Cerebral RevascularizationMoyamoya DiseaseStrokeAdolescentChildHumansRetrospective StudiesTreatment OutcomeVascular Surgical ProceduresMoyamoyaOutcomesPediatricRevascularizationTiming

Identifiers

PMID36930272
PMCPMC11008696
OpenAlexW4327683197

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