Evidence map›Paper›PMID 36929744›Full record

ArticleACS sensors2023

Smart Bandaid Integrated with Fully Textile OECT for Uric Acid Real-Time Monitoring in Wound Exudate.

Danilo Arcangeli, Isacco Gualandi, Federica Mariani, Marta Tessarolo, Francesca Ceccardi, Francesco Decataldo, Federico Melandri, Domenica Tonelli, Beatrice Fraboni, Erika Scavetta

Open access · hybridAbstract read
In one paragraph

Article in ACS sensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
7.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 70 citations in OpenAlex.

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  18. Use of Wireless Smart Devices in Remote Monitoring of Chronic Wounds: A Scoping Review.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Danilo ArcangeliDepartment of Industrial Chemistry "Toso Montanari", University of Bologna, Viale Risorgimento 4, 40136 Bologna, Italy.
Isacco GualandiDepartment of Industrial Chemistry "Toso Montanari", University of Bologna, Viale Risorgimento 4, 40136 Bologna, Italy.
Federica MarianiDepartment of Industrial Chemistry "Toso Montanari", University of Bologna, Viale Risorgimento 4, 40136 Bologna, Italy.ORCID 0000-0001-6293-3920
Marta TessaroloDepartment of Physics and Astronomy "Augusto Righi", University of Bologna, Viale Berti Pichat 6/2, 40127 Bologna, Italy.
Francesca CeccardiDepartment of Industrial Chemistry "Toso Montanari", University of Bologna, Viale Risorgimento 4, 40136 Bologna, Italy.
Francesco DecataldoDepartment of Physics and Astronomy "Augusto Righi", University of Bologna, Viale Berti Pichat 6/2, 40127 Bologna, Italy.ORCID 0000-0002-0669-7369
Federico MelandriPlastod S.p.A., Via Walter Masetti 7, Calderara di Reno, 40012 Bologna, Italy.
Domenica TonelliDepartment of Industrial Chemistry "Toso Montanari", University of Bologna, Viale Risorgimento 4, 40136 Bologna, Italy.ORCID 0000-0002-2844-9817
Beatrice FraboniDepartment of Physics and Astronomy "Augusto Righi", University of Bologna, Viale Berti Pichat 6/2, 40127 Bologna, Italy.ORCID 0000-0002-4875-3816
Erika ScavettaDepartment of Industrial Chemistry "Toso Montanari", University of Bologna, Viale Risorgimento 4, 40136 Bologna, Italy.ORCID 0000-0001-7298-0528
University of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hard-to-heal wounds (i.e., severe and/or chronic) are typically associated with particular pathologies or afflictions such as diabetes, immunodeficiencies, compression traumas in bedridden people, skin grafts, or third-degree burns. In this situation, it is critical to constantly monitor the healing stages and the overall wound conditions to allow for better-targeted therapies and faster patient recovery. At the moment, this operation is performed by removing the bandages and visually inspecting the wound, putting the patient at risk of infection and disturbing the healing stages. Recently, new devices have been developed to address these issues by monitoring important biomarkers related to the wound health status, such as pH, moisture, etc. In this contribution, we present a novel textile chemical sensor exploiting an organic electrochemical transistor (OECT) configuration based on poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) for uric acid (UA)-selective monitoring in wound exudate. The combination of special medical-grade textile materials provides a passive sampling system that enables the real-time and non-invasive analysis of wound fluid: UA was detected as a benchmark analyte to monitor the health status of wounds since it represents a relevant biomarker associated with infections or necrotization processes in human tissues. The sensors proved to reliably and reversibly detect UA concentration in synthetic wound exudate in the biologically relevant range of 220-750 μM, operating in flow conditions for better mimicking the real wound bed. This forerunner device paves the way for smart bandages integrated with real-time monitoring OECT-based sensors for wound-healing evaluation.

Indexed as

BandagesUric AcidExudates and TransudatesHumansOrganic ChemicalsTextilesOrganic ChemicalsUric Acidbioelectronicsnon-enzymaticOECTorganic electrochemical transistorPEDOT:PSSsensorsmart dressingtextileuric acid sensingwearablewound healing

Identifiers

PMID36929744
PMCPMC10152490
OpenAlexW4327682149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.