Evidence map›Paper›PMID 36929321›Full record

Trial reportAIDS and behavior2023

Injection Drug Use and Sexual Risk Behaviors Among People who Inject Drugs in Ukraine: A Random-Intercept Latent Transition Analysis.

John Mark Wiginton, Robert Booth, Lisa A Eaton, Laramie R Smith, Cristina Espinosa da Silva, Thomas L Patterson, Eileen V Pitpitan

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in AIDS and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

John Mark WigintonDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California-San Diego, La Jolla, CA, USA. jwiginton@ucsd.edu.ORCID http://orcid.org/0000-0001-9358-7899
Robert BoothDepartment of Psychiatry, University of Colorado School of Medicine, 13001 E 17th Place, Fitzsimons Building, 2nd Floor, Suite C2000, Aurora, CO, 80045, USA.
Lisa A EatonDepartment of Human Development and Family Sciences, University of Connecticut, Family Studies Building, Storrs, CT, 06279, USA.
Laramie R SmithDivision of Infectious Diseases and Global Public Health, School of Medicine, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Cristina Espinosa da SilvaHerbert Wertheim School of Public Health & Human Longevity Science, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Thomas L PattersonDepartments of Medicine and Psychiatry, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Eileen V PitpitanSchool of Social Work, College of Health and Human Services, San Diego State University, 5500 Campanile Dr, San Diego, CA, 92182, USA.
San Diego State University · USUniversity of California San Diego · USUniversity of Colorado Denver · USUniversity of Connecticut · US

Funding

VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SUSAN JANET LITTLE · 1994 to 2026
$78.4M
Training Program in Substance Use, HIV and Related InfectionsT32DA023356 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Natasha Martin, Steffanie A Strathdee · 2007 to 2026
$7.8M
Estimating Mediation and Moderation Effects in HIV Incidence Prevention TrialsR01DA042666 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PITPITAN, EILEEN VIRTUSIO · 2018 to 2022
$2.6M
Peer Leaders as HIV Risk Reduction Change Agents Among IDUs in UkraineR01DA026739 · NIDA · UNIVERSITY OF COLORADO DENVER · PI BOOTH, ROBERT EDWIN · 2010 to 2014
$2.4M
NIAID NIH HHS P30 AI036214NIDA NIH HHS R01 DA026739NIDA NIH HHS R01 DA042666NIDA NIH HHS R01DA042666NIDA NIH HHS T32 DA023356NIDA NIH HHS T32DA023356
6 · The paper itself

Abstract

HIV transmission in Ukraine is driven in part by unsafe injection drug use and sexual risk behaviors among people who inject drugs. We performed a random-intercept latent transition analysis on responses to 9 binary injection drug use and sexual behavior items from 1195 people who inject drugs with negative HIV status enrolled in a clustered randomized clinical trial of a social network intervention in Odessa, Donetsk, and Nikolayev, Ukraine. We identified 5 baseline classes: "Social injection/equipment-sharing" (11.7%), "Social injection" (25.9%), "High-risk collective preparation/splitting" (17.0%), "Collective preparation/splitting" (11.3%), and "Dealer-facilitated injection" (34.1%). After 12 months, intervention participants were more likely to transition to the "Collective preparation/splitting" class, which featured the fewest risk behaviors. Transitioning from the "Collective preparation/splitting" to the "Social injection/equipment-sharing" class was associated with HIV acquisition for control participants. Research to illuminate the stability of these patterns and how they may benefit from uniquely tailored programming to reduce unsafe behaviors is needed.

Indexed as

Drug UsersHIV InfectionsSubstance Abuse, IntravenousHumansNonoxynolRisk-TakingSexual BehaviorUkraineNonoxynolHIVLatent transition analysisPeople who inject drugsSocial network intervention

Identifiers

PMID36929321
PMCPMC10019801
OpenAlexW4327555966

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.