Evidence map›Paper›PMID 36929320›Full record

Trial reportAIDS and behavior2023

The Effect of the Shikamana Peer-and-Provider Intervention on Depressive Symptoms, Alcohol Use, and Other Drug Use Among Gay, Bisexual, and Other Men Who Have Sex with Men in Kenya.

Nicholas R Graff, Chenglin Hong, Brandon Guthrie, Murugi Micheni, Oscar Chirro, Elizabeth Wahome, Elise van der Elst, Eduard J Sanders, Jane M Simoni, Susan M Graham

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 5 countries.

Nicholas R Graff *Department of Epidemiology, University of Washington, 325 Ninth Avenue, Box 359909, Seattle, WA, 98104, USA.
Chenglin Hong *Department of Social Welfare, UCLA Luskin School of Public Affairs, Los Angeles, CA, USA.
Brandon GuthrieDepartment of Epidemiology, University of Washington, 325 Ninth Avenue, Box 359909, Seattle, WA, 98104, USA.
Murugi MicheniNational AIDS Control Council, Nairobi, Kenya.
Oscar ChirroKEMRI - Wellcome Trust Research Programme, Kilifi, Kenya.
Elizabeth WahomeKEMRI - Wellcome Trust Research Programme, Kilifi, Kenya.
Elise van der ElstKEMRI - Wellcome Trust Research Programme, Kilifi, Kenya.
Eduard J SandersKEMRI - Wellcome Trust Research Programme, Kilifi, Kenya.
Jane M SimoniDepartment of Global Health, University of Washington, 325 Ninth Avenue, Box 359909, Seattle, WA, 98104, USA.
Susan M GrahamDepartment of Epidemiology, University of Washington, 325 Ninth Avenue, Box 359909, Seattle, WA, 98104, USA. grahamsm@uw.edu.ORCID http://orcid.org/0000-0001-7847-8686
Kenya Medical Research Institute · KEUniversity of Washington · USNational Aids Control Council · KE

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
University of Washington Developmental AIDS Research Center for Mental Health (UW ARCH)P30MH123248 · NIMH · UNIVERSITY OF WASHINGTON · PI SIMONI, JANE M. · 2021 to 2024
$5.8M
Provider and Peer Support Intervention to Improve ART Adherence among Kenyan MenR34MH099946 · NIMH · UNIVERSITY OF WASHINGTON · PI GRAHAM, SUSAN MARIE · 2013 to 2015
$627k
NIAID NIH HHS P30 AI027757NIH HHS R34MH099946NIMH NIH HHS P30 MH123248NIMH NIH HHS P30MH123248NIMH NIH HHS R34 MH099946Wellcome Trust
6 · The paper itself

Abstract

Kenyan gay, bisexual, and other men who have sex with men (GBMSM) face stigma and discrimination, which may adversely impact mental health and limit antiretroviral therapy (ART) adherence among GBMSM living with HIV. We evaluated whether the Shikamana peer-and-provider intervention, which improved ART adherence among participants in a small randomized trial, was associated with changes in mental health or substance use. The intervention was associated with a significant decrease in PHQ-9 score between baseline and month 6 (estimated change - 2.7, 95% CI - 5.2 to - 0.2, p = 0.037) compared to standard care. In an exploratory analysis, each one-point increment in baseline HIV stigma score was associated with a - 0.7 point (95% CI - 1.3 to - 0.04, p = 0.037) greater decrease in PHQ-9 score over the study period in the intervention group. Additional research is required to understand factors that influence this intervention's effects on mental health outcomes.

Indexed as

HIV InfectionsSexual and Gender MinoritiesSubstance-Related DisordersAnti-Retroviral AgentsDepressionHomosexuality, MaleHumansKenyaMaleAnti-Retroviral AgentsDepressionHIVKenyaMental healthMen who have sex with menStigma

Identifiers

PMID36929320
PMCPMC10504414
OpenAlexW4327574688

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.