Evidence map›Paper›PMID 36928781›Full record

ArticleNature human behaviour2023

Structural and functional asymmetry of the neonatal cerebral cortex.

Logan Z J Williams, Sean P Fitzgibbon, Jelena Bozek, Anderson M Winkler, Ralica Dimitrova, Tanya Poppe, Andreas Schuh, Antonios Makropoulos, John Cupitt, Jonathan O'Muircheartaigh and 8 more

Open access · greenAbstract readComparative Study
In one paragraph

Article in Nature human behaviour, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 5 countries.

Logan Z J WilliamsCentre for the Developing Brain, Department of Perinatal Imaging and Health, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK. logan.williams@kcl.ac.uk.ORCID 0000-0001-5392-7043
Sean P FitzgibbonCentre for Functional MRI of the Brain (FMRIB), Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Jelena BozekFaculty of Electrical Engineering and Computing, University of Zagreb, Zagreb, Croatia.ORCID 0000-0002-5986-5442
Anderson M WinklerEmotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-4169-9781
Ralica DimitrovaCentre for the Developing Brain, Department of Perinatal Imaging and Health, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Tanya PoppeCentre for the Developing Brain, Department of Perinatal Imaging and Health, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Andreas SchuhDepartment of Computing, Imperial College London, London, UK.ORCID 0000-0002-8214-116X
Antonios MakropoulosCentre for the Developing Brain, Department of Perinatal Imaging and Health, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
John CupittDepartment of Computing, Imperial College London, London, UK.
Jonathan O'MuircheartaighCentre for the Developing Brain, Department of Perinatal Imaging and Health, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Eugene P DuffCentre for Functional MRI of the Brain (FMRIB), Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Lucilio Cordero-GrandeCentre for the Developing Brain, Department of Perinatal Imaging and Health, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.ORCID 0000-0003-1477-304X
Anthony N PriceCentre for the Developing Brain, Department of Perinatal Imaging and Health, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Joseph V HajnalCentre for the Developing Brain, Department of Perinatal Imaging and Health, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Daniel RueckertDepartment of Computing, Imperial College London, London, UK.
Stephen M SmithCentre for Functional MRI of the Brain (FMRIB), Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UK.
A David EdwardsCentre for the Developing Brain, Department of Perinatal Imaging and Health, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.ORCID 0000-0003-4801-7066
Emma C RobinsonCentre for the Developing Brain, Department of Perinatal Imaging and Health, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK. emma.robinson@kcl.ac.uk.ORCID 0000-0002-7886-3426
King's College London · GBJohn Radcliffe Hospital · GBImperial College London · GBNational Institutes of Health · USTUM Klinikum · DEUniversity of Zagreb · HR

Funding

Academy of Medical Sciences SBF003/111Medical Research Council MR/K006355/1Medical Research Council MR/N026063/1Medical Research Council MR/W006251/1Wellcome Trust 206675/Z/17/Z
6 · The paper itself

Abstract

Features of brain asymmetry have been implicated in a broad range of cognitive processes; however, their origins are still poorly understood. Here we investigated cortical asymmetries in 442 healthy term-born neonates using structural and functional magnetic resonance images from the Developing Human Connectome Project. Our results demonstrate that the neonatal cortex is markedly asymmetric in both structure and function. Cortical asymmetries observed in the term cohort were contextualized in two ways: by comparing them against cortical asymmetries observed in 103 preterm neonates scanned at term-equivalent age, and by comparing structural asymmetries against those observed in 1,110 healthy young adults from the Human Connectome Project. While associations with preterm birth and biological sex were minimal, significant differences exist between birth and adulthood.

Indexed as

Cerebral CortexFunctional LateralityAuditory PathwaysBirth WeightCohort StudiesConnectomeFemaleGestational AgeHealthHumansInfant, NewbornInfant, PrematureMagnetic Resonance ImagingMaleNerve NetVisual Pathways

Identifiers

PMID36928781
PMCPMC7618908
OpenAlexW4327569182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.