Evidence map›Paper›PMID 36928724›Full record

ArticlePloS one2023

A single center experience of adjusting valve pressure ventriculoperitoneal shunts for the treatment of hydrocephalus in infants under 6 months old.

Adriano Cattani, Franziska Schwarzer, Mario Schwarzer, Andrea Spyrantis, Gerhard Marquardt, Susanne Schubert-Bast, Volker Seifert, Thomas M Freiman

Open access · goldFull text read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Adriano CattaniDepartment of Neurosurgery, Goethe-University Hospital, Frankfurt am Main, Germany.ORCID 0000-0002-3698-0800
Franziska SchwarzerDepartment of Neurosurgery, Goethe-University Hospital, Frankfurt am Main, Germany.
Mario SchwarzerDepartment of Neuropaediatrics, Goethe-University Hospital, Frankfurt am Main, Germany.
Andrea SpyrantisDepartment of Neurosurgery, Goethe-University Hospital, Frankfurt am Main, Germany.
Gerhard MarquardtDepartment of Neurosurgery, Goethe-University Hospital, Frankfurt am Main, Germany.
Susanne Schubert-BastDepartment of Neuropaediatrics, Goethe-University Hospital, Frankfurt am Main, Germany.ORCID 0000-0003-1545-7364
Volker SeifertDepartment of Neurosurgery, Goethe-University Hospital, Frankfurt am Main, Germany.
Thomas M FreimanDepartment of Neurosurgery, Goethe-University Hospital, Frankfurt am Main, Germany.ORCID 0000-0002-2591-2829
Goethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVentriculoperitoneal shunt (VPS) with adjustable differential pressure valves are commonly used to treat infants with hydrocephalus avoiding shunt related under- or overdrainage. The aim of this study was to analyse the influence of VPS adjustable differential pressure valve on the head circumference (HC) and ventricular size (VS) stabilization in infants with post intraventricular haemorrhage, acquired and congenital hydrocephali.

methodsForty-three hydrocephalic infants under 6 months old were prospectively included between 2014 and 2018. All patients were treated using a VPS with adjustable differential pressure valve. HC and transfontanelle ultrasonographic VS measurements were regularly performed and pressure valve modifications were done aiming HC and VS percentiles between the 25th and 75th. The patients were divided into two groups: infants with hydrocephalus due to an intraventricular haemorrhage (IVH-H), and infants with hydrocephalus due to other aetiologies (OAE-H).

resultsThe mean of pressure valve modification was 3.7 per patient in the IVH-H group, versus 2.95 in the OAE-H group. The median of last pressure valve value was higher at 8.5 cm H2O in the IVH-H group comparing to 5 cm H2O in the OAE-H group (p = 0.013).

conclusionOptimal VPS pressure valve values could be extremely difficult to settle in order to gain normalisation of the HC and VS in infants. However, after long term follow up (mean of 18 months) and several pressure valve modifications, this normalisation is possible and shows that infants with IVH-H need a higher pressure valve value comparing to infants with OAE-H.

Indexed as

HydrocephalusVentriculoperitoneal ShuntCerebral HemorrhageCerebrospinal Fluid ShuntsHumansInfantRetrospective StudiesTreatment Outcome

Identifiers

PMID36928724
PMCPMC10019726
OpenAlexW4327565256

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read46
identifiers read7
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.