Evidence map›Paper›PMID 36928721›Full record

ArticlePloS one2023

Design considerations for a hierarchical semantic compositional framework for medical natural language understanding.

Ricky K Taira, Anders O Garlid, William Speier

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Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ricky K TairaMedical and Imaging Informatics (MII) Group, Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, California, United States of America.ORCID 0000-0001-9754-8993
Anders O GarlidMedical and Imaging Informatics (MII) Group, Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, California, United States of America.ORCID 0000-0002-1665-678X
William SpeierMedical and Imaging Informatics (MII) Group, Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, California, United States of America.

Funding

BioCADDIE: Biomedical and healthCAre Data Discovery and Indexing Engine centerU24AI117966 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OHNO-MACHADO, LUCILA · 2014 to 2016
$10.9M
Predicting Diabetic Retinopathy from Risk Factor Data and Digital Retinal ImagesR01LM012309 · NLM · CHARLES R. DREW UNIVERSITY OF MED & SCI · PI DASKIVICH, LAUREN, GEORGE, SHEBA · 2016 to 2022
$2.8M
Individually-tailored clinical decision support for management of indeterminate pulmonary nodulesR01CA226079 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ABERLE, DENISE R., BUI, ALEX · 2019 to 2023
$2.3M
Role of IGF-IR tyrosine kinase in NPM-ALK-expressing T-cell lymphomaR01CA151533 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI AMIN, HESHAM M · 2011 to 2015
$1.6M
RUMI: A patient portal for retrieving understandable medical informationR01LM011333 · NLM · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BUI, ALEX · 2012 to 2015
$1.3M
NCI NIH HHS R01 CA151533NCI NIH HHS R01 CA226079NIAID NIH HHS U24 AI117966NLM NIH HHS R01 LM011333NLM NIH HHS R01 LM012309
6 · The paper itself

Abstract

Medical natural language processing (NLP) systems are a key enabling technology for transforming Big Data from clinical report repositories to information used to support disease models and validate intervention methods. However, current medical NLP systems fall considerably short when faced with the task of logically interpreting clinical text. In this paper, we describe a framework inspired by mechanisms of human cognition in an attempt to jump the NLP performance curve. The design centers on a hierarchical semantic compositional model (HSCM), which provides an internal substrate for guiding the interpretation process. The paper describes insights from four key cognitive aspects: semantic memory, semantic composition, semantic activation, and hierarchical predictive coding. We discuss the design of a generative semantic model and an associated semantic parser used to transform a free-text sentence into a logical representation of its meaning. The paper discusses supportive and antagonistic arguments for the key features of the architecture as a long-term foundational framework.

Indexed as

SemanticsSoftwareBig DataHumansNatural Language Processing

Identifiers

PMID36928721
PMCPMC10019629

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.