Evidence map›Paper›PMID 36928567›Full record

ArticleEuropean radiology2023

Ultrafast MRI using deep learning echoplanar imaging for a comprehensive assessment of acute ischemic stroke.

Sebastien Verclytte, Robin Gnanih, Stephane Verdun, Thorsten Feiweier, Bryan Clifford, Khalid Ambarki, Marta Pasquini, Juliette Ding

Abstract read
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In one paragraph

Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Sebastien VerclytteImaging Department, Lille Catholic Hospitals, Lille Catholic University, F-59000, Lille, France. verclytte.sebastien@ghicl.net.ORCID http://orcid.org/0000-0002-3312-1904
Robin GnanihImaging Department, Lille Catholic Hospitals, Lille Catholic University, F-59000, Lille, France.
Stephane VerdunBiostatistics Department - Delegation for Clinical Research and Innovation, Lille Catholic Hospitals, Lille Catholic University, F-59000, Lille, France.
Thorsten FeiweierSiemens Healthcare GmbH, Erlangen, Germany.
Bryan CliffordSiemens Medical Solutions USA, Boston, MA, USA.
Khalid AmbarkiSiemens Healthcare SAS, 93200, Saint-Denis, France.
Marta PasquiniDepartment of Neurology, Lille Catholic Hospitals, Lille Catholic University, F-59000, Lille, France.
Juliette DingImaging Department, Lille Catholic Hospitals, Lille Catholic University, F-59000, Lille, France.
Université Catholique de Lille · FRSiemens (France) · FRSiemens Healthineers (Germany) · DESiemens (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAcute ischemic stroke (AIS) is an emergency requiring both fast and informative MR sequences. We aimed to assess the performance of an artificial intelligence-enhanced ultrafast (UF) protocol, compared to the reference protocol, in the AIS management.

methodsWe included patients admitted in the emergency department for suspected AIS. Each patient underwent a 3-T MR protocol, including reference acquisitions of T2-FLAIR, DWI, and SWI (duration: 7 min 54 s) and their accelerated multishot EPI counterparts for T2-FLAIR and T2*, complemented by a single-shot EPI DWI (duration: 1 min 54 s). Two blinded neuroradiologists reviewed each dataset, assessing DWI (detection, location, number of acute lesions), FLAIR (vascular hyperintensities, visibility of acute lesions), and SWI/T2* (hemorrhagic transformation, thrombus). We compared the agreement between the diagnoses obtained with both protocols using kappa coefficients.

resultsA total of 173 patients were included consecutively, of whom 80 with an AIS in DWI. We found an almost perfect agreement between the UF and reference protocols regarding the detection, distribution, number of AIS in DWI (κ = 0.98, 0.98, and 0.87 respectively), the presence of vascular hyperintensities, and the presence of a parenchymal hyperintensity in the AIS region in FLAIR (κ = 0.93 and 0.89 respectively). Agreement was substantial in T2*/SWI for thrombus detection, and fair for hemorrhagic transformation detection (κ = 0.64 and 0.38 respectively). Differential diagnoses were similarly detected by both protocols (κ = 1).

conclusionsOur AI-enhanced ultrafast MRI protocol allowed an effective detection and characterization of both AIS and differential diagnoses in less than 2 min. KEY POINTS: • The AI-enhanced ultrafast MRI protocol allowed an effective detection of acute stroke. • Characterization of stroke features with the UF protocol was equivalent to the reference sequences. • Differential diagnoses were detected similarly by the UF and reference protocols.

Indexed as

Deep LearningIschemic StrokeStrokeArtificial IntelligenceDiffusion Magnetic Resonance ImagingEcho-Planar ImagingHumansMagnetic Resonance ImagingArtificial intelligenceIschemic strokeMagnetic resonance imaging

Identifiers

PMID36928567
OpenAlexW4327679260

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.