Evidence map›Paper›PMID 36928552›Full record

SynthesisInternational orthopaedics2023

Incidence of total hip arthroplasty in patients with Legg-Calve-Perthes disease after conservative or surgical treatment: a meta-analysis.

Xinwang Zhi, Huimei Wu, Chenyu Xiang, Jianqun Wang, Yeya Tan, Chun Zeng, Hongwen Xu, Federico Canavese

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in International orthopaedics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Legg-Calvé-Perthes disease- surgical treatment options.Archives of orthopaedic and trauma surgery · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Xinwang Zhi *Department of Pediatric Orthopedics, GuangZhou Women and Children's Medical Center, 9 Jinsui Road, Guangzhou, 510623, China.
Huimei Wu *School of Pediatrics, Guangzhou Medical University, Xinzao, Guangzhou, 510000, China.
Chenyu Xiang *School of Pediatrics, Guangzhou Medical University, Xinzao, Guangzhou, 510000, China.
Jianqun WangDepartment of Pediatric Orthopedics, GuangZhou Women and Children's Medical Center, 9 Jinsui Road, Guangzhou, 510623, China.
Yeya TanGuangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Chun ZengAcademy of Orthopedics, Guangdong Province, Department of Orthopedics, The Third Affiliated Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Hongwen Xu *Department of Pediatric Orthopedics, GuangZhou Women and Children's Medical Center, 9 Jinsui Road, Guangzhou, 510623, China. xuhongwen@gwcmc.org.
Federico Canavese *Department of Pediatric Orthopedics, GuangZhou Women and Children's Medical Center, 9 Jinsui Road, Guangzhou, 510623, China. canavese_federico@yahoo.fr.ORCID http://orcid.org/0000-0002-6114-5372
Guangzhou Medical University · CNGuangzhou Women and Children Medical Center · CNThird Affiliated Hospital of Southern Medical University · CNHôpital Jeanne de Flandre · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis systematic review and meta-analysis aimed to determine the incidence of total hip arthroplasty (THA) in patients with Legg-Calve-Perthes disease (LCPD) treated conservatively or surgically and factors influencing the incidence of THA.

methodsLong-term follow-up studies on the conservative or surgical treatments of LCPD from 1950 to 2021 were conducted using six public databases. Articles were screened by two investigators (PRISMA guidelines), and the quality of the included publications (n = 27) was assessed (MINORS criteria). R version 4.2.1 was used for statistical analysis.

resultsThe overall incidences of THA were 6.8% and 5.14% in patients who were treated conservatively and surgically, respectively. At disease onset, the incidences of THA were 6.79% and 6.17% after conservative treatment and surgery in patients aged < seven years, respectively, and 16.97% and 3.61% in patients aged > seven years, respectively. The incidences of THA were 4.91%, 5.19%, and 23.18% in patients who were treated conservatively with ≤ 30, 30-40, and > 40 years of follow-up, respectively, and 3.68%, 3.11%, 9.66%, and 17.92% in patients who were treated surgically with ≤ ten, ten to 20, 20-40, and > 40 years of follow-up, respectively. In patients who received conservative treatment, the incidences of THA were 5.79% and 5.29% in patients with Stulberg I-II and III-V, respectively. In surgically treated patients, the incidence of THA was 0% in Stulberg I-II and 8% in Stulberg III-V.

conclusionPatients with LCPD had relatively low incidences of THA. The greater the age at disease onset and longer the follow-up, the higher the incidence of THA; however, the Stulberg classification was not directly associated with the incidence of THA.

Indexed as

Arthroplasty, Replacement, HipLegg-Calve-Perthes DiseaseHumansIncidenceRetrospective StudiesTreatment OutcomeConservative treatmentLegg-Calve-Perthes diseaseMeta-analysisSurgical treatmentTotal hip arthroplasty

Identifiers

PMID36928552
OpenAlexW4327545491

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.