Evidence map›Paper›PMID 36928536›Full record

ArticleCancer causes & control : CCC2023

The association between poor oral health and risk of breast cancer in the UK Biobank.

Zeni Wu, Fangyu Li, Jian Sang, Gretchen L Gierach, Emily Vogtmann

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer causes & control : CCC, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zeni WuDivision of Cancer Epidemiology and Genetics, National Cancer Institute, 9609 Medical Center Dr, MSC 9768, Bethesda, MD, 20892, USA.
Fangyu LiDivision of Cancer Epidemiology and Genetics, National Cancer Institute, 9609 Medical Center Dr, MSC 9768, Bethesda, MD, 20892, USA.
Jian SangDivision of Cancer Epidemiology and Genetics, National Cancer Institute, 9609 Medical Center Dr, MSC 9768, Bethesda, MD, 20892, USA.
Gretchen L GierachDivision of Cancer Epidemiology and Genetics, National Cancer Institute, 9609 Medical Center Dr, MSC 9768, Bethesda, MD, 20892, USA.
Emily VogtmannDivision of Cancer Epidemiology and Genetics, National Cancer Institute, 9609 Medical Center Dr, MSC 9768, Bethesda, MD, 20892, USA. emily.vogtmann@nih.gov.
Division of Cancer Epidemiology and GeneticsNational Cancer Institute · US

Funding

Intramural NIH HHS Z99 CA999999NIH HHS Intramural Research Program
6 · The paper itself

Abstract

purposeSpecific oral health conditions may be risk factors for breast cancer. This study aimed to investigate the associations of oral health conditions with breast cancer risk.

methodsA total of 234,363 women from the UK Biobank prospective cohort were included in this study. We examined the association of self-reported painful/bleeding gums, loose teeth, mouth ulcers, toothache, and use of dentures with the risk of breast cancer. Hazard ratios (HRs) and 95% confidence intervals (95% CIs) for the associations were calculated with adjustment for multiple confounders.

resultsNo associations of self-reported painful/bleeding gums (HR = 1.04, 95% CI 0.98-1.10), loose teeth (HR = 0.92, 95% CI 0.82-1.02), mouth ulcers (HR = 0.99, 95% CI 0.93-1.06), toothache (HR = 1.03, 95% CI 0.92-1.14), or denture use (HR = 0.96, 95% CI 0.91-1.02) with breast cancer risk were found. No statistical heterogeneity was observed in analyses stratified by baseline smoking and menopausal status.

conclusionWe observed no association between self-reported oral health conditions with the risk of breast cancer. Additional research with clinical examinations or oral health biomarkers in diverse populations is warranted.

Indexed as

Breast NeoplasmsMouth DiseasesOral UlcerBiological Specimen BanksFemaleHumansOral HealthProspective StudiesRisk FactorsToothacheUnited KingdomBreast cancerLoose teethMouth ulcersPeriodontal diseaseToothache

Identifiers

PMID36928536
PMCPMC11112745
OpenAlexW4327682039

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.