ArticlePain and therapy2023
Transcutaneous Electrical Acupoint Stimulation Improves Postoperative Sleep Quality in Patients Undergoing Laparoscopic Gastrointestinal Tumor Surgery: A Prospective, Randomized Controlled Trial.
Article in Pain and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Efficacy of electroacupuncture for insomnia in cancer patients: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- Effect of transcutaneous electrical acupoint stimulation on perioperative hypothermia in video-assisted thoracoscopic surgery: a randomized controlled trial.Frontiers in medicine · 2026Trial
- Preoperative Transcutaneous Electrical Acupoint Stimulation Alleviates Postoperative Pain and Improves Sleep Quality in Breast Cancer Patients with Preoperative Sleep Disturbance: A Partially Randomized Controlled Trial.Journal of pain research · 2026Trial
- Combining electroacupuncture and transcutaneous electrical acupoint stimulation for psychiatric disorders in women victims of domestic violence: An assessor-blinded, randomised controlled trial.General psychiatry · 2026Article
- Role of gamma-aminobutyric acid-ergic neurons in the thalamic reticular nucleus in regulating sleep-wake cycles in mice treated with acupuncture for insomnia.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026Article
- Mapping the Global Surge in Postoperative Sleep Research From 2014 to 2024: Bibliometric Analysis.Interactive journal of medical research · 2026Article
- Acupuncture-related peripheral stimulation as a candidate neuromodulatory model of insomnia: clinical evidence, sleep-wake circuitry, and translational limits.Frontiers in neuroscience · 2026Review
- Insomnia Pathogenesis and Multidimensional Mechanisms of Acupuncture: A Narrative Review.International journal of general medicine · 2026Review
- Effect of linearly polarized light irradiation near stellate ganglion on postoperative sleep disorders in patients undergoing modified radical mastectomy of breast cancer.Perioperative medicine (London, England) · 2025Article
- Effects of programs on sleep improvement in shift-work nurses: a systematic review and meta-analysis.BMC nursing · 2025Article
- Effects of gastrointestinal motility therapy combined with acupuncture on gastrointestinal function in patients after laparoscopic radical surgery.World journal of gastrointestinal surgery · 2025Article
- Electro-Acupuncture Therapy Alleviates Post-Stroke Insomnia by Regulating Sirt1 and the Nrf2-ARE Pathway.Neuromolecular medicine · 2025Article
- Research progress on the mechanism of transcutaneous electrical acupoint stimulation in the perioperative period.Frontiers in neurology · 2025Review
- Effect of Transcutaneous Electrical Acupoint Stimulation on Postoperative Sleep Disorders in Older Patients After Urologic Laparoscopic Surgery by Regulating Intestinal Microbiota: Study Protocol for a Prospective Controlled Trial.Nature and science of sleep · 2025Article
- Trends and Emerging Research Areas in Postoperative Sleep Disturbances: A Bibliometric Analysis.Nature and science of sleep · 2025Article
- Clinical study of electroacupuncture on the recovery of gastrointestinal dysfunction after laparoscopic surgery for gastrointestinal cancer - study protocol for a randomized controlled trial.BMC complementary medicine and therapies · 2024Article
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
Abstract
introductionThis study was conducted to observe the effect of transcutaneous electrical acupoint stimulation (TEAS) on the postoperative sleep quality of patients undergoing gastrointestinal tumor surgery and to verify the possible mechanism.
methodsEighty-three patients were allocated to the TEAS or Sham group. Patients in the TEAS group received TEAS treatment (disperse-dense waves; frequency, 2/100 Hz) on bilateral Shenmen (HT7), Neiguan (PC6) and Zusanli (ST36) points for 30 min each time, total three times in the perioperative period. In the Sham group, electrodes were placed; however, no current was given. Sleep quality was assessed on the day before surgery (P1) and the first and third days after surgery (D1 and D3) using the Pittsburgh Sleep Quality Index (PSQI) and Athens Insomnia Scale (AIS). Postoperative pain was assessed using visual analog scale (VAS) 72 h postoperatively. The incidences of abdominal distension, dizziness, postoperative nausea and vomiting (PONV) and pulmonary complications were recorded. Serum levels of inflammatory cytokines and the expression of key factors of oxidative stress and key molecules of the nuclear factor erythroid 2-related factor 2/antioxidant response element (Nrf2/ARE) signal pathway were measured.
resultsTEAS ameliorated sleep quality at D1 and D3 (PSQI P < 0.05, AIS P < 0.05) and decreased postoperative pain as demonstrated by lower VAS scores compared to the Sham group (P < 0.05). The incidences of abdominal distension and PONV were also lower in the TEAS group. Markers of oxidative stress were increased (P < 0.05), and the serum concentration of interleukin-6 (IL-6) was significantly lower in the TEAS group. The key mediators of the Nrf2/ARE pathway were enhanced after TEAS.
conclusionPerioperative TEAS improved postoperative sleep quality, reduced postoperative pain and alleviated postoperative adverse effects in patients undergoing laparoscopic gastrointestinal tumor surgery resection. This may be associated with activating Nrf2/ARE signal pathway and decreasing its inflammatory actions.
trial registrationChinese Clinical Trial Registry ( http://www.chictr.org.cn/index.aspx ), ChiCTR2100054971.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.