Evidence map›Paper›PMID 36928026›Full record

ArticleNature microbiology2023

Hyperactive nanobacteria with host-dependent traits pervade Omnitrophota.

Cale O Seymour, Marike Palmer, Eric D Becraft, Ramunas Stepanauskas, Ariel D Friel, Frederik Schulz, Tanja Woyke, Emiley Eloe-Fadrosh, Dengxun Lai, Jian-Yu Jiao and 12 more

Abstract read
In one paragraph

Article in Nature microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Cale O SeymourSchool of Life Sciences, University of Nevada, Las Vegas, Las Vegas, NV, USA.
Marike PalmerSchool of Life Sciences, University of Nevada, Las Vegas, Las Vegas, NV, USA.
Eric D BecraftBigelow Laboratory for Ocean Sciences, East Boothbay, ME, USA.
Ramunas StepanauskasBigelow Laboratory for Ocean Sciences, East Boothbay, ME, USA.ORCID 0000-0003-4458-3108
Ariel D FrielSchool of Life Sciences, University of Nevada, Las Vegas, Las Vegas, NV, USA.
Frederik SchulzDOE Joint Genome Institute, Berkeley, CA, USA.ORCID 0000-0002-4932-4677
Tanja WoykeDOE Joint Genome Institute, Berkeley, CA, USA.ORCID 0000-0002-9485-5637
Emiley Eloe-FadroshDOE Joint Genome Institute, Berkeley, CA, USA.ORCID 0000-0002-8162-1276
Dengxun LaiSchool of Life Sciences, University of Nevada, Las Vegas, Las Vegas, NV, USA.ORCID 0000-0001-8761-7844
Jian-Yu JiaoState Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-Sen University, Guangzhou, People's Republic of China.
Zheng-Shuang HuaDepartment of Environmental Science and Engineering, University of Science and Technology of China, Hefei, People's Republic of China.ORCID 0000-0002-2405-4228
Lan LiuState Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-Sen University, Guangzhou, People's Republic of China.ORCID 0000-0001-8139-7246
Zheng-Han LianState Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-Sen University, Guangzhou, People's Republic of China.
Wen-Jun LiState Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-Sen University, Guangzhou, People's Republic of China.ORCID 0000-0002-1233-736X
Maria ChuvochinaAustralian Centre for Ecogenomics, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia.
Brianna K FinleyCenter for Ecosystem Science and Society (ECOSS), Northern Arizona University, Flagstaff, AZ, USA.
Benjamin J KochCenter for Ecosystem Science and Society (ECOSS), Northern Arizona University, Flagstaff, AZ, USA.ORCID 0000-0002-1914-7681
Egbert SchwartzCenter for Ecosystem Science and Society (ECOSS), Northern Arizona University, Flagstaff, AZ, USA.
Paul DijkstraCenter for Ecosystem Science and Society (ECOSS), Northern Arizona University, Flagstaff, AZ, USA.
Duane P MoserSchool of Life Sciences, University of Nevada, Las Vegas, Las Vegas, NV, USA.
Bruce A HungateCenter for Ecosystem Science and Society (ECOSS), Northern Arizona University, Flagstaff, AZ, USA.ORCID 0000-0002-7337-1887
Brian P HedlundSchool of Life Sciences, University of Nevada, Las Vegas, Las Vegas, NV, USA. brian.hedlund@unlv.edu.ORCID 0000-0001-8530-0448

Funding

National Science Foundation (NSF) 1516679National Science Foundation (NSF) 1826734National Science Foundation (NSF) 1928924
6 · The paper itself

Abstract

Candidate bacterial phylum Omnitrophota has not been isolated and is poorly understood. We analysed 72 newly sequenced and 349 existing Omnitrophota genomes representing 6 classes and 276 species, along with Earth Microbiome Project data to evaluate habitat, metabolic traits and lifestyles. We applied fluorescence-activated cell sorting and differential size filtration, and showed that most Omnitrophota are ultra-small (~0.2 μm) cells that are found in water, sediments and soils. Omnitrophota genomes in 6 classes are reduced, but maintain major biosynthetic and energy conservation pathways, including acetogenesis (with or without the Wood-Ljungdahl pathway) and diverse respirations. At least 64% of Omnitrophota genomes encode gene clusters typical of bacterial symbionts, suggesting host-associated lifestyles. We repurposed quantitative stable-isotope probing data from soils dominated by andesite, basalt or granite weathering and identified 3 families with high isotope uptake consistent with obligate bacterial predators. We propose that most Omnitrophota inhabit various ecosystems as predators or parasites.

Indexed as

Calcifying NanoparticlesMicrobiotaBacteriaHumansCalcifying Nanoparticles

Identifiers

PMID36928026
PMCPMC10066038

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.