Evidence map›Paper›PMID 36927856›Full record

ArticleThe Journal of veterinary medical science2023

Agarose gel electrophoresis pattern of serum creatine kinase and lactate dehydrogenase isoenzymes in zoo-managed Asian elephants (Elephas maximus).

Kazuya Takehana, Mare Adachi, Shingo Ishikawa, Norio Yamagishi

Open access · diamondAbstract read
In one paragraph

Article in The Journal of veterinary medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kazuya TakehanaIchihara Elephant Kingdom Zoological Park, Chiba, Japan.
Mare AdachiDepartment of Veterinary Science, School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, Japan.
Shingo IshikawaDepartment of Veterinary Science, School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, Japan.
Norio YamagishiDepartment of Veterinary Science, School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, Japan.
Osaka Prefecture University · JPTokyo Zoological Park Society · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum levels of creatine kinase (CK) and lactate dehydrogenase (LDH) isoenzymes were evaluated in nine zoo-managed Asian elephants (Elephas maximus) using a commercial agarose gel electrophoresis (AGE) kit. CK was separated into two major fractions, CK-BB and CK-MM, along with a small fraction of macroenzyme-CK type 2 (mCK2); CK-MM was the largest fraction. LDH was separated into five fractions (LDH1-5); LDH3 was the largest fraction. Age was negatively and positively correlated with the percentages of CK-BB and CK-MM, respectively, and negatively correlated with CK-BB and mCK2 activities. These results indicate that an AGE kit can be used to evaluate CK and LDH isoenzymes. Routine isoenzyme testing may enable early detection of disease and physiological changes.

Indexed as

ElephantsAnimalsCreatine KinaseElectrophoresis, Agar GelIsoenzymesL-Lactate DehydrogenaseCreatine KinaseIsoenzymesL-Lactate Dehydrogenaseagarose gel electrophoresis (AGE)Asian elephants (Elephas maximus)creatine kinase (CK)isoenzymelactate dehydrogenase (LDH)

Identifiers

PMID36927856
PMCPMC10209465
OpenAlexW4324117650

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.