Evidence map›Paper›PMID 36927718›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2023

Spatiotemporal spread of tick-borne encephalitis in the EU/EEA, 2012 to 2020.

Jasper Van Heuverswyn, Luisa K Hallmaier-Wacker, Julien Beauté, Joana Gomes Dias, Joana M Haussig, Kristina Busch, Jana Kerlik, Mateusz Markowicz, Henna Mäkelä, Teresa Marie Nygren and 5 more

Full text read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

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  16. Identifying hotspots and risk factors for tick-borne encephalitis virus emergence at its range margins to guide interventions, Great Britain.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jasper Van HeuverswynEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Luisa K Hallmaier-WackerEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Julien BeautéEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Joana Gomes DiasEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Joana M HaussigEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Kristina BuschPublic Health Agency of Sweden, Stockholm, Sweden.
Jana KerlikRegional Authority of Public Health in Banská Bystrica, Banská Bystrica, Slovakia.
Mateusz MarkowiczAustrian Agency for Health and Food Safety, Vienna, Austria.
Henna MäkeläFinnish Institute for Health and Welfare, Helsinki, Finland.
Teresa Marie NygrenRobert Koch Institute (RKI), Berlin, Germany.
Hana OrlíkováNational Institute of Public Health, Prague, Czechia.
Maja SocanNational Institute of Public Health, Ljubljana, Slovenia.
Jakub ZbrzeźniakNational Institute of Public Health - NIH - National Research Institute, Warsaw, Poland.
Milda ŽygutieneNational Public Health Center under the Ministry of Health, Vilnius, Lithuania.
Céline M GossnerEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundTick-borne encephalitis (TBE) is a vaccine-preventable disease involving the central nervous system. TBE became a notifiable disease on the EU/EEA level in 2012.AimWe aimed to provide an updated epidemiological assessment of TBE in the EU/EEA, focusing on spatiotemporal changes.MethodsWe performed a descriptive analysis of case characteristics, time and location using data of human TBE cases reported by EU/EEA countries to the European Centre for Disease Prevention and Control with disease onset in 2012-2020. We analysed data at EU/EEA, national, and subnational levels and calculated notification rates using Eurostat population data. Regression models were used for temporal analysis.ResultsFrom 2012 to 2020, 19 countries reported 29,974 TBE cases, of which 24,629 (98.6%) were autochthonous. Czechia, Germany and Lithuania reported 52.9% of all cases. The highest notification rates were recorded in Lithuania, Latvia, and Estonia (16.2, 9.5 and 7.5 cases/100,000 population, respectively). Fifty regions from 10 countries, had a notification rate ≥ 5/100,000. There was an increasing trend in number of cases during the study period with an estimated 0.053 additional TBE cases every week. In 2020, 11.5% more TBE cases were reported than predicted based on data from 2016 to 2019. A geographical spread of cases was observed, particularly in regions situated north-west of known endemic regions.ConclusionA close monitoring of ongoing changes to the TBE epidemiological situation in Europe can support the timely adaption of vaccination recommendations. Further analyses to identify populations and geographical areas where vaccination programmes can be of benefit are needed.

Indexed as

Encephalitis, Tick-BorneViral VaccinesEuropeGermanyHumansVaccinationViral VaccinesepidemiologyEuropean Unionpublic healthsurveillanceTick-borne encephalitisvaccination

Identifiers

PMID36927718
PMCPMC10021474

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.