Evidence map›Paper›PMID 36927589›Full record

ArticleBMJ open2023

Factors influencing influenza, pneumococcal and shingles vaccine uptake and refusal in older adults: a population-based cross-sectional study in England.

Pui San Tan, Martina Patone, Ashley Kieran Clift, Hajira Dambha-Miller, Defne Saatci, Tom A Ranger, Cesar Garriga, Francesco Zaccardi, Baiju R Shah, Carol Coupland and 3 more

Open access · goldFull text read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Pui San Tan *Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK pui.tan@phc.ox.ac.uk.ORCID 0000-0003-3359-1874
Martina Patone *Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.ORCID 0000-0001-5954-1045
Ashley Kieran Clift *Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-0061-979X
Hajira Dambha-MillerPrimary Care Research Centre, University of Southampton Faculty of Medicine, Southampton, UK.
Defne SaatciNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Tom A RangerNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.ORCID 0000-0003-3091-2337
Cesar GarrigaNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.ORCID 0000-0001-7073-3611
Francesco ZaccardiUniversity of Leicester, Leicester, UK.
Baiju R ShahSunnybrooke Health Sciences Centre, Toronto, Ontario, Canada.
Carol CouplandDivision of Primary Care, University of Nottingham, Nottingham, UK.
Simon J GriffinThe Primary Care Unit, University of Cambridge, Cambridge, UK.
Kamlesh KhuntiDiabetes Research Centre, University of Leicester, Leicester, UK.
Julia Hippisley-CoxNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-2479-7283
University of Oxford · GBUniversity of Leicester · GBSunnybrook Health Science Centre · CAUniversity of Cambridge · GBUniversity of Nottingham · GBUniversity of Southampton · GB

Funding

Cancer Research UK C2195/A31310Cancer Research UK C5255/A18085Medical Research Council MC_UU_00006/6Medical Research Council MC_UU_12015/4Medical Research Council MR/V027778/1Wellcome TrustWellcome Trust 204826/Z/16/Z
6 · The paper itself

Abstract

objectivesUptake of influenza, pneumococcal and shingles vaccines in older adults vary across regions and socioeconomic backgrounds. In this study, we study the coverage and factors associated with vaccination uptake, as well as refusal in the unvaccinated population and their associations with ethnicity, deprivation, household size and health conditions. DESIGN, SETTING AND

participantsThis is a cross-sectional study of adults aged 65 years or older in England, using a large primary care database. Associations of vaccine uptake and refusal in the unvaccinated with ethnicity, deprivation, household size and health conditions were modelled using multivariable logistic regression. OUTCOME MEASURE: Influenza, pneumococcal and shingles vaccine uptake and refusal (in the unvaccinated).

resultsThis study included 2 054 463 patients from 1318 general practices. 1 711 465 (83.3%) received at least one influenza vaccine, 1 391 228 (67.7%) pneumococcal vaccine and 690 783 (53.4%) shingles vaccine. Compared with White ethnicity, influenza vaccine uptake was lower in Chinese (OR 0.49; 95% CI 0.45 to 0.53), 'Other ethnic' groups (0.63; 95% CI 0.60 to 0.65), black Caribbean (0.68; 95% CI 0.64 to 0.71) and black African (0.72; 95% CI 0.68 to 0.77). There was generally lower vaccination uptake among more deprived individuals, people living in larger household sizes (three or more persons) and those with fewer health conditions. Among those who were unvaccinated, higher odds of refusal were associated with the black Caribbean ethnic group and marginally with increased deprivation, but not associated with higher refusal in those living in large households or those with lesser health conditions.

conclusionCertain ethnic minority groups, deprived populations, large households and 'healthier' individuals were less likely to receive a vaccine, although higher refusal was only associated with ethnicity and deprivation but not larger households nor healthier individuals. Understanding these may inform tailored public health messaging to different communities for equitable implementation of vaccination programmes.

Indexed as

Herpes ZosterHerpes Zoster VaccineInfluenza, HumanInfluenza VaccinesAgedCross-Sectional StudiesEthnicityHumansMinority GroupsPneumococcal VaccinesStreptococcus pneumoniaeHerpes Zoster VaccineInfluenza VaccinesPneumococcal VaccinesEpidemiologyEPIDEMIOLOGYPRIMARY CAREPublic health

Identifiers

PMID36927589
PMCPMC10030484
OpenAlexW4327626944

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read55
identifiers read1
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.