Observational studyBMC ophthalmology2023
Corneal higher order aberrations by Sirius topography and their relation to different refractive errors.
Observational study in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06278220 (Scheimpflug Versus Placido-disc System in Evaluation of Corneal Higher-Order Aberrations Before and After LASIK), which is not on this map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Scheimpflug Versus Placido-disc System in Evaluation of Corneal Higher-Order Aberrations Before and After LASIK
Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- Corneal higher-order aberrations in early-onset cataract patients without identifiable risk factors: a retrospective case-control study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Association between Fibrovascular Translucency of Pterygium and Corneal Curvature and Aberrations after Adjustment for Horizontal Invasion Length.Korean journal of ophthalmology : KJO · 2026Article
- Frequency-dependent associations of contrast sensitivity and corneal aberrations after SMILE PRO in eyes with high astigmatism.Frontiers in medicine · 2026Article
- Corneal epithelial aberrations: a novel diagnostic tool for keratoconus and forme fruste keratoconus.Eye and vision (London, England) · 2025Article
- Sirius Cutting Mode enhances vision and reduces myopia severity through personalized treatment.American journal of translational research · 2025Article
- Associations between refractive error components and higher-order aberrations in simple myopia and compound myopic astigmatism.Frontiers in ophthalmology · 2025Article
- Influence of Biometric and Corneal Tomographic Parameters on Normative Corneal Aberrations Measured by Root Mean Square.Journal of clinical medicine · 2024Article
- Characteristics and influencing factors of corneal higher-order aberrations in patients with cataract.BMC ophthalmology · 2023Article
- Presbyopia intraocular lens in aberrated corneas.Taiwan journal of ophthalmologyReview
- Evaluation of Ocular Higher-Order Aberrations in Patients with Migraine: A Comparative Study.Romanian journal of ophthalmologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare the root mean square (RMS) of anterior corneal higher-order aberrations (HOAs) in ametropic and emmetropic eyes.
methodsThis retrospective observational study was conducted at the Department of Ophthalmology, Tishreen University Hospital, Latakia, Syria. Study eyes were divided into four groups based on refractive error: mild-to-moderate myopia, hypermetropia, myopic astigmatism, and emmetropic eyes as controls. The following anterior corneal HOAs were evaluated using the Scheimpflug-Placido Sirius (CSO, Italy) tomographer over 6 mm pupil: Root mean square (RMS) total corneal HOAs, RMS trefoil, RMS coma and RMS spherical aberrations.
resultsRMS values of total HOAs, trefoil and coma showed statistically significant differences in all four groups (P < 0.05, all). HOAs were noted to be lowest in the control group (0.18 ± 0.09, 011 ± 0.08 and 0.09 ± 0.08 μm, respectively) and highest in the myopic astigmatism group (0.31 ± 0.16, 0.15 ± 0.12, 0.17 ± 0.14 μm, respectively). RMS spherical aberration was lowest in the astigmatism group (0.00 ± 0.16 μm) with a statistically significant difference from that in the control group (0.05 ± 0.07 μm, P = 0.049).
conclusionThe mean RMS values of total HOAs, trefoil and coma were highest in the astigmatism group and lowest in the control group. However, spherical aberration was minimal in the astigmatism group. A better understanding and targeted treatment of higher-order aberrations in ametropic human eyes, and in particular eyes with astigmatism, may enhance visual quality and performance in the treatment of refractive errors. Recognising atypical HOAs may also assist in the early detection of pathological conditions such as keratoconus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.