Evidence map›Paper›PMID 36927172›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2023

Superior sagittal sinus flow as a proxy for tracking global cerebral blood flow dynamics during wakefulness and sleep.

Alessandra S Caporale, Alexander M Barclay, Jing Xu, Hengyi Rao, Hyunyeol Lee, Michael C Langham, John A Detre, Felix W Wehrli

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Alessandra S CaporaleLaboratory for Structural, Physiological, and Functional Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Alexander M BarclayLaboratory for Structural, Physiological, and Functional Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Jing XuLaboratory for Structural, Physiological, and Functional Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Hengyi RaoDepartment of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Hyunyeol LeeLaboratory for Structural, Physiological, and Functional Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Michael C LanghamLaboratory for Structural, Physiological, and Functional Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
John A DetreLaboratory for Structural, Physiological, and Functional Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Felix W WehrliLaboratory for Structural, Physiological, and Functional Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
University of Pennsylvania · USKyungpook National University · KRUniversity of Chieti-Pescara · IT

Funding

Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
High Spatial and Temporal Resolution MRI Mapping of Oxygen Consumption in HumansP41EB029460 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Ravinder Reddy · 2021 to 2026
$7.6M
Training in Structural, Physiologic and Functional MRIT32EB020087 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI JAMES C GEE, Chamith Sudesh Rajapakse · 2016 to 2026
$2.1M
Neural correlates of cognitive fatigue and bright light treatment in older adultsR21AG051981 · NIA · UNIVERSITY OF PENNSYLVANIA · PI RAO, HENGYI · 2018 to 2019
$443k
Noninvasive Quantification of Age-Related Alterations in Sleep-Dependent CMRO2 Attenuation Using EEG-Correlated MRIR21AG065816 · NIA · UNIVERSITY OF PENNSYLVANIA · PI WEHRLI, FELIX W · 2020 to 2021
$442k
NCATS NIH HHS UL1 TR001878NIA NIH HHS R21 AG051981NIA NIH HHS R21 AG065816NIBIB NIH HHS P41 EB029460NIBIB NIH HHS T32 EB020087
6 · The paper itself

Abstract

Sleep, a state of reduced consciousness, affects brain oxygen metabolism and lowers cerebral metabolic rate of oxygen (CMRO

Indexed as

Superior Sagittal SinusWakefulnessBrainCerebrovascular CirculationHumansMagnetic Resonance ImagingOxygenOxygen ConsumptionSleepOxygencerebral blood flowdual-band OxFlowEEG correlated MRIneurovascular couplingsleepstate-dependent CMRO2

Identifiers

PMID36927172
PMCPMC10369151
OpenAlexW4327682515

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.