ArticleCirculation research2023
Enhanced Ca
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Article in Circulation research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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48citing papers in PubMed
13.4field-weighted citation impact, top 1% of its field
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Who cites it
48 citing papers in PubMed, 61 citations in OpenAlex.
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- Phosphatase Inhibition Attenuates the Negative Inotropic Effect of Muscarinic Receptors in the Presence of Serotonin.Current issues in molecular biology · 2026Article
- Restoration of mitochondrial CaJournal of molecular and cellular cardiology · 2026Article
- Computational modelling of the pro- and antiarrhythmic effects of atrial high rate-dependent trafficking of small-conductance calcium-activated potassium channels.The Journal of physiology · 2026Article
- Prospective in silico trials identify combined SK and KThe Journal of physiology · 2026Article
- The clinical pathophysiology of atrial fibrillation: outstanding questions from bedside to bench and back.Physiological reviews · 2026Review
- Mild Neonatal Hypoxia Targets Synaptic Maturation, Disrupts Adult Hippocampal Learning and Memory, and Is Associated with CK2-Mediated Loss of Synaptic Calcium-Activated Potassium Channel KCNN2 Activity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Cytosolic calcium handling signature: integration with clinical predictors enhances prediction of post-operative atrial fibrillation.European heart journal · 2026Article
- Arrhythmia-induced cardiomyopathy: focus on atrial fibrillation.Nature reviews. Cardiology · 2026Review
- Colchicine in atrial fibrillation: mechanisms, highlights, and current evidence.Frontiers in pharmacology · 2026Review
- The exquisite link between potassium homeostasis regulation and cardiovascular health: exploration and analysis.Frontiers in physiology · 2026Review
- Atrial Cardiomyopathy and Atrial Fibrillation in Different Heart Failure Substrates.Arrhythmia & electrophysiology review · 2026Review
- The mechanism of electrical remodeling in atrial fibrillation and current research status of natural drugs and active ingredients inhibiting atrial electrical remodeling.Frontiers in cardiovascular medicine · 2026Review
- Article
- Thyrotropin Directly Affects Cardiac Electrophysiology and Is Associated With AF Prevalence.Circulation. Arrhythmia and electrophysiology · 2025Article
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Authors and funding
18 authors at 10 institutions in 8 countries.
Jordi HeijmanInstitute of Pharmacology, West German Heart and Vascular Center, Faculty of Medicine, University Duisburg-Essen, Germany (J.H., C.E.M., I.H.A.-T., M.T., Y.Z., S.D., A.S., S.N., D.D.).ORCID 0000-0002-1418-108X
Xiaobo ZhouFirst Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany (X.Z.).ORCID 0000-0002-5895-0127
Stefano MorottiDepartment of Pharmacology, University of California, Davis (S.M., E.G.).ORCID 0000-0001-8679-665X
Cristina E MolinaInstitute of Pharmacology, West German Heart and Vascular Center, Faculty of Medicine, University Duisburg-Essen, Germany (J.H., C.E.M., I.H.A.-T., M.T., Y.Z., S.D., A.S., S.N., D.D.).ORCID 0000-0003-3094-1568
Issam H Abu-TahaInstitute of Pharmacology, West German Heart and Vascular Center, Faculty of Medicine, University Duisburg-Essen, Germany (J.H., C.E.M., I.H.A.-T., M.T., Y.Z., S.D., A.S., S.N., D.D.).ORCID 0000-0002-2298-8959
Marcel TekookInstitute of Pharmacology, West German Heart and Vascular Center, Faculty of Medicine, University Duisburg-Essen, Germany (J.H., C.E.M., I.H.A.-T., M.T., Y.Z., S.D., A.S., S.N., D.D.).
Thomas JespersenDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (T.J., A.S.).
Yiqiao ZhangInstitute of Pharmacology, West German Heart and Vascular Center, Faculty of Medicine, University Duisburg-Essen, Germany (J.H., C.E.M., I.H.A.-T., M.T., Y.Z., S.D., A.S., S.N., D.D.).ORCID 0000-0001-5059-1329
Shokoufeh DobrevInstitute of Pharmacology, West German Heart and Vascular Center, Faculty of Medicine, University Duisburg-Essen, Germany (J.H., C.E.M., I.H.A.-T., M.T., Y.Z., S.D., A.S., S.N., D.D.).
Hendrik MiltingErich and Hanna Klessmann Institute, Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum, Bad Oeynhausen, Germany (H.M., J.G.).ORCID 0000-0001-9722-0007
Jan GummertErich and Hanna Klessmann Institute, Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum, Bad Oeynhausen, Germany (H.M., J.G.).
Matthias KarckDepartment of Cardiac Surgery, Heidelberg University Hospital, Germany (M. Karck).
Markus KamlerDepartment of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen, University Hospital Essen, Germany (M. Kamler).
Ali El-ArmoucheInstitute of Pharmacology, Dresden University of Technology, Germany (A.E.-A.).ORCID 0000-0003-2514-9429
Arnela SaljicInstitute of Pharmacology, West German Heart and Vascular Center, Faculty of Medicine, University Duisburg-Essen, Germany (J.H., C.E.M., I.H.A.-T., M.T., Y.Z., S.D., A.S., S.N., D.D.).
Eleonora GrandiDepartment of Pharmacology, University of California, Davis (S.M., E.G.).
Stanley NattelInstitute of Pharmacology, West German Heart and Vascular Center, Faculty of Medicine, University Duisburg-Essen, Germany (J.H., C.E.M., I.H.A.-T., M.T., Y.Z., S.D., A.S., S.N., D.D.).ORCID 0000-0002-5565-3311
Dobromir DobrevInstitute of Pharmacology, West German Heart and Vascular Center, Faculty of Medicine, University Duisburg-Essen, Germany (J.H., C.E.M., I.H.A.-T., M.T., Y.Z., S.D., A.S., S.N., D.D.).ORCID 0000-0002-4612-117X
West German Heart and Vascular Center Essen · DEHeart and Diabetes Center North Rhine-Westphalia · DEHeidelberg University · DEUniversity of California, Davis · USUniversity of Copenhagen · DKBaylor College of Medicine · USMaastricht University · NLMontreal Heart Institute · CATechnische Universität Dresden · DEUniversität Hamburg · DE
Funding
Project 3 (Mercola)P01HL141084 · NHLBI · STANFORD UNIVERSITY · PI MARK MERCOLA · 2019 to 2026
$21.1MRyanodine receptor regulation in post-operative atrial fibrillationR01HL089598 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI WEHRENS, XANDER H.T. · 2007 to 2022
$6.5MDevelopment of the Predictive NeuroCardiovascular SimulatorOT2OD026580 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CLANCY, COLLEEN E, GRANDI, ELEONORA · 2018 to 2021
$5.7MThe Role of Inflammasome in the Pathogenesis of Atrial FibrillationR01HL136389 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI Na Li · 2017 to 2026
$5.6MSex-specific arrhythmogenic mechanisms of atrial fibrillationR01HL131517 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Eleonora Grandi · 2016 to 2026
$5.0MFunctional Microdomains in the Heart's Pacemaker: A New Dimension of Cardiac RemodelingR01HL141214 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Alexey V Glukhov · 2018 to 2026
$3.8MCardiac fibroblast inflammasome and atrial myopathyR01HL163277 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI LI, NA · 2022 to 2025
$2.8MRole of Nucleoside-Diphosphate Kinase Signaling in Atrial FibrillationR01HL160992 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI Xander H.T. Wehrens · 2023 to 2026
$2.1MModeling of subcellular signaling crosstalk in failing myocytesR00HL138160 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MOROTTI, STEFANO · 2020 to 2022
$722kNHLBI NIH HHS P01 HL141084NHLBI NIH HHS R00 HL138160NHLBI NIH HHS R01 HL089598NHLBI NIH HHS R01 HL131517NHLBI NIH HHS R01 HL136389NHLBI NIH HHS R01 HL141214NHLBI NIH HHS R01 HL160992NHLBI NIH HHS R01 HL163277NIH HHS OT2 OD026580
Abstract
backgroundSmall-conductance Ca
methodsApamin-sensitive SK-channel current (I
resultsI
conclusionsI
Indexed as
Atrial FibrillationAction PotentialsAnimalsAnti-Arrhythmia AgentsApaminCalmodulinHeart AtriaHumansMyocytes, CardiacPrimaquineSmall-Conductance Calcium-Activated Potassium ChannelsAnti-Arrhythmia AgentsApaminCalmodulinPrimaquineSmall-Conductance Calcium-Activated Potassium Channelsactininapaminatrial fibrillationatrial remodelingcalmodulinprotein phosphatase-2Aprotein transport
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.