Evidence map›Paper›PMID 36926933›Full record

ArticleJournal of the American Heart Association2023

Impact of Neuroeffector Adrenergic Receptor Polymorphisms on Incident Ventricular Fibrillation During Acute Myocardial Ischemia.

Philippe Chevalier, Pascal Roy, Francis Bessière, Elodie Morel, Bénédicte Ankou, Gina Morgan, Indrani Halder, Barry London, Wayne A Minobe, Dobromir Slavov and 12 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Observational
  2. βmedRxiv : the preprint server for health sciences · 2025
    Article
  3. Putative role of TMEM165 in congenital cardiomyopathies.Frontiers in molecular neuroscience · 2025
    Review
  4. Review
  5. βJournal of the American Heart Association · 2023
    Article
4 · The record

Corrections and comments

  • Commented on by
    β2023
5 · Who and what money

Authors and funding

22 authors at 9 institutions in 2 countries.

Philippe ChevalierRhythmology Department Hospital Louis Pradel Lyon France.ORCID 0000-0001-8185-2229
Pascal RoyHospices Civils de Lyon, Services Biostatistiques Lyon France.ORCID 0000-0003-3837-3198
Francis BessièreRhythmology Department Hospital Louis Pradel Lyon France.ORCID 0000-0002-3642-9795
Elodie MorelRhythmology Department Hospital Louis Pradel Lyon France.ORCID 0000-0001-8943-1760
Bénédicte AnkouRhythmology Department Hospital Louis Pradel Lyon France.
Gina MorganDivision of Cardiovascular Medicine University of Iowa Iowa City IA.ORCID 0000-0003-2579-1657
Indrani HalderDivision of Cardiovascular Medicine University of Iowa Iowa City IA.
Barry LondonDivision of Cardiovascular Medicine University of Iowa Iowa City IA.ORCID 0000-0003-1506-3947
Wayne A MinobeDivision of Cardiology University of Colorado Anschutz Medical Campus Aurora CO.ORCID 0000-0001-8257-2368
Dobromir SlavovDivision of Cardiology University of Colorado Anschutz Medical Campus Aurora CO.
Antoine DelinièreRhythmology Department Hospital Louis Pradel Lyon France.ORCID 0000-0002-3742-9674
Thomas BochatonDepartment of Intensive Cardiac Care Hospital Louis Pradel Lyon France.ORCID 0000-0002-5889-7506
Franck PaganelliDepartment of Cardiology Hôpital Nord Marseille France.ORCID 0000-0001-7322-9816
Nathalie LesavreDepartment of Cardiology Hôpital Nord Marseille France.
Clément BoiteuxRhythmology Department Hospital Louis Pradel Lyon France.ORCID 0000-0001-5905-0596
Jacques MansouratiCardiology Department Hôpital de La Cavale Blanche, Brest University Hospital Brest France.
Philippe MauryCardiology Department University Hospital Rangueil Toulouse France.ORCID 0000-0002-4800-1841
Gaël ClericiCardiology Department Saint Pierre University Hospital La Réunion France.ORCID 0000-0002-4631-6196
Pierre François WinumCardiology Department Nîmes University Hospital Nîmes France.
Sophia P HueblerARCA Biopharma Westminster CO.
Ian A CarrollDivision of Cardiology University of Colorado Anschutz Medical Campus Aurora CO.ORCID 0000-0003-2071-5479
Michael R BristowDivision of Cardiology University of Colorado Anschutz Medical Campus Aurora CO.ORCID 0000-0002-8860-4698
Hôpital Louis Pradel · FRARCA Biopharma (United States) · USUniversity of Iowa · USHôpital Nord · FRUniversity of Colorado Anschutz Medical Campus · USHôpital Rangueil · FRHospices Civils de Lyon · FRUniversité Claude Bernard Lyon 1 · FRUniversité de Nîmes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Cardiac adrenergic receptor gene polymorphisms have the potential to influence risk of developing ventricular fibrillation (VF) during ST-segment-elevation myocardial infarction, but no previous study has comprehensively investigated those most likely to alter norepinephrine release, signal transduction, or biased signaling. Methods and Results In a case-control study, we recruited 953 patients with ST-segment-elevation myocardial infarction without previous cardiac history, 477 with primary VF, and 476 controls without VF, and genotyped them for

Indexed as

ST Elevation Myocardial InfarctionVentricular FibrillationCase-Control StudiesHumansNorepinephrinePolymorphism, GeneticReceptors, AdrenergicNorepinephrineReceptors, Adrenergicacute myocardial infarctionadrenergic receptor polymorphismsSTEMIsudden cardiac deathventricular fibrillation

Identifiers

PMID36926933
PMCPMC10111522
OpenAlexW4327590131

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.