Evidence map›Paper›PMID 36926925›Full record

ArticleJournal of the American Heart Association2023

Epiphenomenon or Prognostically Relevant Interventional Target? A Novel Proportionality Framework for Severe Tricuspid Regurgitation.

Vera Fortmeier, Mark Lachmann, Matthias Unterhuber, Lukas Stolz, Mohammad Kassar, Laurin Ochs, Muhammed Gerçek, Anne R Schöber, Thomas J Stocker, Hazem Omran and 14 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 8 institutions in 3 countries.

Vera FortmeierDepartment of General and Interventional Cardiology, Heart and Diabetes Center North Rhine-Westphalia Ruhr University Bochum Bad Oeynhausen Germany.ORCID 0000-0001-6477-7829
Mark LachmannFirst Department of Medicine, Klinikum rechts der Isar Technical University of Munich Munich Germany.ORCID 0000-0002-1798-550X
Matthias UnterhuberDepartment of Cardiology, Heart Center Leipzig University of Leipzig Leipzig Germany.
Lukas StolzMedizinische Klinik und Poliklinik I Klinikum der Universität München, Ludwig Maximilians University of Munich Munich Germany.ORCID 0000-0002-1362-1493
Mohammad KassarDepartment of Cardiology Inselspital Bern, Bern University Hospital Bern Switzerland.ORCID 0000-0002-7576-2224
Laurin OchsDepartment of Cardiology, Heart Center University of Cologne Cologne Germany.ORCID 0000-0001-7079-9856
Muhammed GerçekDepartment of General and Interventional Cardiology, Heart and Diabetes Center North Rhine-Westphalia Ruhr University Bochum Bad Oeynhausen Germany.ORCID 0000-0002-1822-936X
Anne R SchöberDepartment of Cardiology, Heart Center Leipzig University of Leipzig Leipzig Germany.
Thomas J StockerDZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance Munich Germany.ORCID 0000-0003-3579-0113
Hazem OmranDepartment of General and Interventional Cardiology, Heart and Diabetes Center North Rhine-Westphalia Ruhr University Bochum Bad Oeynhausen Germany.ORCID 0000-0001-7342-3686
Maria I KörberDepartment of Cardiology, Heart Center University of Cologne Cologne Germany.ORCID 0000-0001-9073-9279
Amelie HesseFirst Department of Medicine, Klinikum rechts der Isar Technical University of Munich Munich Germany.ORCID 0000-0003-0535-9197
Kai Peter FriedrichsDepartment of General and Interventional Cardiology, Heart and Diabetes Center North Rhine-Westphalia Ruhr University Bochum Bad Oeynhausen Germany.ORCID 0000-0001-9546-3048
Shinsuke YuasaDepartment of Cardiology Keio University School of Medicine Tokyo Japan.ORCID 0000-0001-5593-7552
Tanja K RudolphDepartment of General and Interventional Cardiology, Heart and Diabetes Center North Rhine-Westphalia Ruhr University Bochum Bad Oeynhausen Germany.ORCID 0000-0001-8839-7476
Michael JonerDZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance Munich Germany.ORCID 0000-0002-2971-8310
Roman PfisterDepartment of Cardiology, Heart Center University of Cologne Cologne Germany.ORCID 0000-0002-4358-5008
Stephan BaldusDepartment of Cardiology, Heart Center University of Cologne Cologne Germany.ORCID 0000-0001-8259-1737
Karl-Ludwig LaugwitzFirst Department of Medicine, Klinikum rechts der Isar Technical University of Munich Munich Germany.ORCID 0000-0003-4948-4846
Fabien PrazDepartment of Cardiology Inselspital Bern, Bern University Hospital Bern Switzerland.
Stephan WindeckerDepartment of Cardiology Inselspital Bern, Bern University Hospital Bern Switzerland.ORCID 0000-0003-2653-6762
Jörg HausleiterDZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance Munich Germany.ORCID 0000-0003-2909-7961
Philipp LurzDepartment of Cardiology, Heart Center Leipzig University of Leipzig Leipzig Germany.ORCID 0000-0002-5993-4487
Volker RudolphDepartment of General and Interventional Cardiology, Heart and Diabetes Center North Rhine-Westphalia Ruhr University Bochum Bad Oeynhausen Germany.ORCID 0000-0001-5385-6839
Heart and Diabetes Center North Rhine-Westphalia · DEUniversity of Cologne · DELeipzig Heart Institute · DELMU Klinikum · DETUM Klinikum · DEUniversity Hospital of Bern · CHGerman Centre for Cardiovascular Research · DEKeio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Tricuspid regurgitation (TR) frequently develops in patients with long-standing pulmonary hypertension, and both pathologies are associated with increased morbidity and mortality. This study aimed to improve prognostic assessment in patients with severe TR undergoing transcatheter tricuspid valve intervention (TTVI) by relating the extent of TR to pulmonary artery pressures. Methods and Results In this multicenter study, we included 533 patients undergoing TTVI for moderate-to-severe or severe TR. The proportionality framework was based on the ratio of tricuspid valve effective regurgitant orifice area to mean pulmonary artery pressure. An optimal threshold for tricuspid valve effective regurgitant orifice area/mean pulmonary artery pressure ratio was derived on 353 patients with regard to 2-year all-cause mortality and externally validated on 180 patients. Patients with a tricuspid valve effective regurgitant orifice area/mean pulmonary artery pressure ratio ≤1.25 mm

Indexed as

Hypertension, PulmonaryTricuspid Valve InsufficiencyHumansPrognosisTreatment OutcomeTricuspid Valvepulmonary hypertensiontranscatheter tricuspid valve interventiontricuspid regurgitation

Identifiers

PMID36926925
PMCPMC10111550
OpenAlexW4327544447

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.