Evidence map›Paper›PMID 36926823›Full record

ArticleACS applied materials & interfaces2023

Synthesis and Characterization of Nitric Oxide-Releasing Ampicillin as a Potential Strategy for Combatting Bacterial Biofilm Formation.

Lori M Estes Bright, Mark Richard Stephen Garren, Megan Douglass, Hitesh Handa

Open access · hybridAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
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  9. Article
  10. Functionalized MoSJournal of nanobiotechnology · 2023
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lori M Estes BrightSchool of Chemical, Materials, and Biomedical Engineering, University of Georgia, Athens, Georgia 30602, United States.
Mark Richard Stephen GarrenSchool of Chemical, Materials, and Biomedical Engineering, University of Georgia, Athens, Georgia 30602, United States.ORCID 0000-0001-5194-6558
Megan DouglassSchool of Chemical, Materials, and Biomedical Engineering, University of Georgia, Athens, Georgia 30602, United States.
Hitesh HandaSchool of Chemical, Materials, and Biomedical Engineering, University of Georgia, Athens, Georgia 30602, United States.ORCID 0000-0002-9369-7374
University of Georgia · US

Funding

Engineering nitric oxide releasing polymer with immobilized thrombin inhibitor for blood contacting applicationsR01HL134899 · NHLBI · UNIVERSITY OF GEORGIA · PI HANDA, HITESH · 2017 to 2025
$3.0M
NHLBI NIH HHS R01 HL134899
6 · The paper itself

Abstract

Biofilm formation on biomaterial interfaces and the development of antibiotic-resistant bacteria have decreased the effectiveness of traditional antibiotic treatment of infections. In this project, ampicillin, a commonly used antibiotic, was conjugated with

Indexed as

Methicillin-Resistant Staphylococcus aureusNitric OxideAmpicillinAnti-Bacterial AgentsBacteriaBiofilmsS-Nitroso-N-AcetylpenicillamineAmpicillinAnti-Bacterial AgentsNitric OxideS-Nitroso-N-Acetylpenicillamineampicillinantibioticantimicrobialnitric oxideS-nitroso-N-acetylpenicillamine

Identifiers

PMID36926823
PMCPMC10064314
OpenAlexW4327556517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.