Evidence map›Paper›PMID 36926776›Full record

ArticleThe Indian journal of medical research

A retrospective analysis of serological & molecular testing data on dengue fever in Kolkata & adjacent districts during 2016-2019.

Agniva Majumdar, Rajarshi Gupta, Ananya Chatterjee, Hasina Banu, Madhumonti Biswas, Rudrak Gupta, Soumen Mukherjee, Provash Sadhukhan, Shanta Dutta

Abstract read
In one paragraph

Article in The Indian journal of medical research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Agniva MajumdarRegional Virus Research and Diagnostic Laboratory, ICMR-National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India.
Rajarshi GuptaDepartment of Microbiology, Shri Ramkrishna Institute of Medical Sciences & Sanaka Hospitals, Durgapur, West Bengal, India.
Ananya ChatterjeeRegional Virus Research and Diagnostic Laboratory, ICMR-National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India.
Hasina BanuRegional Virus Research and Diagnostic Laboratory, ICMR-National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India.
Madhumonti BiswasRegional Virus Research and Diagnostic Laboratory, ICMR-National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India.
Rudrak GuptaRegional Virus Research and Diagnostic Laboratory, ICMR-National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India.
Soumen MukherjeeRegional Virus Research and Diagnostic Laboratory, ICMR-National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India.
Provash SadhukhanVirus Laboratory, ICMR-National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India.
Shanta DuttaRegional Virus Research and Diagnostic Laboratory, ICMR-National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background & objectives: Regional Virus Research and Diagnostic Laboratory established at ICMR-National Institute of Cholera and Enteric Diseases (NICED) regularly receives samples for dengue screening and serotyping from patients of acute febrile illness (AFI) from Kolkata and adjacent districts. In this study, data over a three year period (August 2016-July 2019) was retrospectively analyzed to provide insight into the epidemiological trends of dengue fever in this region. Methods: Serological screening of dengue was performed by detection of NS1 antigen and/or immunoglobulin M (IgM) antibody. Dengue serotyping was done by conventional or real-time reverse transcriptase-PCR. The data were analyzed to describe the distribution of dengue with respect to age of patient, duration of fever on the day of blood collection and month of the year. Zip codes were used for spatial plotting. Results: Out of the 24,474 samples received from Kolkata and its adjacent districts (Hooghly, Howrah, North and South 24 Parganas), 38.3 per cent (95% confidence interval: 37.7-38.9%) samples were screened positive for dengue. The correlation between age and dengue positivity was found to be weak. A combination of dengue NS1 antigen and dengue IgM antibody detection may be a better option for detecting dengue positivity compared to a single test. Most AFI cases were tested from August to November during the study period, with maximum dengue positivity noted during September (45.9%). The predominant serotype of 2016, dengue virus serotype 1 (DENV-1), was almost entirely replaced by DENV-2 in 2017 and 2018. Interpretation & conclusions: Dengue continues to be an important cause of AFI in the region and round-the-year preventive measures are required for its control. Serotype switching is alarming and should be monitored routinely.

Indexed as

DengueDengue VirusFeverHumansImmunoglobulin MMolecular Diagnostic TechniquesRetrospective StudiesSerogroupImmunoglobulin MDengue feverdengue serotypingKolkatamapping

Identifiers

PMID36926776
PMCPMC10231729

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