Evidence map›Paper›PMID 36926600›Full record

ArticleJAMIA open2023

Understanding pediatric long COVID using a tree-based scan statistic approach: an EHR-based cohort study from the RECOVER Program.

Vitaly Lorman, Suchitra Rao, Ravi Jhaveri, Abigail Case, Asuncion Mejias, Nathan M Pajor, Payal Patel, Deepika Thacker, Seuli Bose-Brill, Jason Block and 7 more

Open access · goldAbstract read
In one paragraph

Article in JAMIA open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Long COVID Incidence Proportion in Adults and Children Between 2020 and 2024: An Electronic Health Record-Based Study From the RECOVER Initiative.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
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  6. Article
  7. Article
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  9. Article
  10. Article
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  12. Pediatric Long COVID Subphenotypes: An EHR-based study from the RECOVER program.medRxiv : the preprint server for health sciences · 2024
    Article
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  15. Review
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  19. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 1 country.

Vitaly LormanApplied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0003-0561-6587
Suchitra RaoDepartment of Pediatrics, University of Colorado School of Medicine and Children's Hospital of Colorado, Aurora, Colorado, USA.
Ravi JhaveriDivision of Infectious Diseases, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0001-9921-0419
Abigail CaseDivision of Physical Medicine & Rehabilitation, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Asuncion MejiasDivision of Infectious Diseases, Department of Pediatrics, Nationwide Children's Hospital and The Ohio State University, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0002-5983-8006
Nathan M PajorDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Payal PatelDepartment of Neurology, University of Washington, Seattle, Washington, USA.
Deepika ThackerNemours Cardiac Center, Nemours Children's Health, Wilmington, Delaware, USA.
Seuli Bose-BrillInternal Medicine and Pediatrics Section, Division of General Internal Medicine, Department of Internal Medicine, Ohio State University College of Medicine and Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Jason BlockDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Pilgrim Health Care Institute, Harvard Medical School, Boston, Massachusetts, USA.
Patrick C HanleyDivision of Endocrinology, Nemours Children's Hospital, Wilmington, Delaware, USA.
Priya PrahaladDivision of Endocrinology, Department of Pediatrics, Stanford University, Stanford, California, USA.ORCID https://orcid.org/0000-0002-3894-4344
Yong ChenDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Christopher B ForrestApplied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
L Charles BaileyApplied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Grace M LeeDivision of Infectious Diseases, Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA.
Hanieh RazzaghiApplied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Children's Hospital of Philadelphia · USStanford University · USChildren's Hospital Colorado · USCincinnati Children's Hospital Medical Center · USHarvard University · USLurie Children's Hospital · USNationwide Children's Hospital · USNemours Children's Health System · USThe Ohio State University Wexner Medical Center · USUniversity of Pennsylvania · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Post-acute sequalae of SARS-CoV-2 infection (PASC) is not well defined in pediatrics given its heterogeneity of presentation and severity in this population. The aim of this study is to use novel methods that rely on data mining approaches rather than clinical experience to detect conditions and symptoms associated with pediatric PASC. Materials and Methods: We used a propensity-matched cohort design comparing children identified using the new PASC ICD10CM diagnosis code (U09.9) ( Results: We found significant enrichment among children with PASC in cardiac, respiratory, neurologic, psychological, endocrine, gastrointestinal, and musculoskeletal systems, the most significant related to circulatory and respiratory such as dyspnea, difficulty breathing, and fatigue and malaise. Discussion: Our study addresses methodological limitations of prior studies that rely on prespecified clusters of potential PASC-associated diagnoses driven by clinician experience. Future studies are needed to identify patterns of diagnoses and their associations to derive clinical phenotypes. Conclusion: We identified multiple conditions and body systems associated with pediatric PASC. Because we rely on a data-driven approach, several new or under-reported conditions and symptoms were detected that warrant further investigation.

Indexed as

COVID-19long COVIDpost-acute sequelae of SARS-CoV-2 infection

Identifiers

PMID36926600
PMCPMC10013630
OpenAlexW4323350133

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.