Evidence map›Paper›PMID 36926556›Full record

ReviewNanoscale advances2023

Functional nano-systems for transdermal drug delivery and skin therapy.

Lijun Liu, Wenbin Zhao, Qingming Ma, Yang Gao, Weijiang Wang, Xuan Zhang, Yunxia Dong, Tingting Zhang, Yan Liang, Shangcong Han and 5 more

Abstract readReview
In one paragraph

Review in Nanoscale advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lijun LiuSchool of Pharmacy, Qingdao University Qingdao 266071 China qma@qdu.edu.cn sunyong@qdu.edu.cn.
Wenbin ZhaoSchool of Pharmacy, Qingdao University Qingdao 266071 China qma@qdu.edu.cn sunyong@qdu.edu.cn.
Qingming MaSchool of Pharmacy, Qingdao University Qingdao 266071 China qma@qdu.edu.cn sunyong@qdu.edu.cn.ORCID https://orcid.org/0000-0001-9026-2706
Yang GaoSchool of Pharmacy, Qingdao University Qingdao 266071 China qma@qdu.edu.cn sunyong@qdu.edu.cn.
Weijiang WangSchool of Pharmacy, Qingdao University Qingdao 266071 China qma@qdu.edu.cn sunyong@qdu.edu.cn.
Xuan ZhangSchool of Pharmacy, Qingdao University Qingdao 266071 China qma@qdu.edu.cn sunyong@qdu.edu.cn.
Yunxia DongSchool of Pharmacy, Qingdao University Qingdao 266071 China qma@qdu.edu.cn sunyong@qdu.edu.cn.
Tingting ZhangSchool of Pharmacy, Qingdao University Qingdao 266071 China qma@qdu.edu.cn sunyong@qdu.edu.cn.
Yan LiangSchool of Pharmacy, Qingdao University Qingdao 266071 China qma@qdu.edu.cn sunyong@qdu.edu.cn.ORCID https://orcid.org/0000-0003-1084-6117
Shangcong HanSchool of Pharmacy, Qingdao University Qingdao 266071 China qma@qdu.edu.cn sunyong@qdu.edu.cn.
Jie CaoSchool of Pharmacy, Qingdao University Qingdao 266071 China qma@qdu.edu.cn sunyong@qdu.edu.cn.
Xinyu WangInstitute of Thermal Science and Technology, Shandong University Jinan 250061 China.ORCID https://orcid.org/0000-0003-4143-334X
Wentao SunSchool of Health and Life Sciences, University of Health and Rehabilitation Sciences Qingdao 266113 China.
Haifeng MaDepartment of Geriatrics, Zibo Municipal Hospital Zibo 255400 China hfma0533@126.com.
Yong SunSchool of Pharmacy, Qingdao University Qingdao 266071 China qma@qdu.edu.cn sunyong@qdu.edu.cn.ORCID https://orcid.org/0000-0003-0365-1151

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transdermal drug delivery is one of the least intrusive and patient-friendly ways for therapeutic agent administration. Recently, functional nano-systems have been demonstrated as one of the most promising strategies to treat skin diseases by improving drug penetration across the skin barrier and achieving therapeutically effective drug concentrations in the target cutaneous tissues. Here, a brief review of functional nano-systems for promoting transdermal drug delivery is presented. The fundamentals of transdermal delivery, including skin biology and penetration routes, are introduced. The characteristics of functional nano-systems for facilitating transdermal drug delivery are elucidated. Moreover, the fabrication of various types of functional transdermal nano-systems is systematically presented. Multiple techniques for evaluating the transdermal capacities of nano-systems are illustrated. Finally, the advances in the applications of functional transdermal nano-systems for treating different skin diseases are summarized.

Identifiers

PMID36926556
PMCPMC10012846

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.