ReviewFrontiers in cell and developmental biology2023
The current regenerative medicine approaches of craniofacial diseases: A narrative review.
Review in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Efficacy of bioactive glass versus traditional bone grafts in maxillofacial reconstruction: A systematic review and meta-analysis of clinical outcomes.Cell transplantationPooled it
- The Impact of Cancer Treatment On Oral Structures and the Facial Part of the Skull - Implications for Prosthetic Treatment and Oncological Risk.Current oncology reports · 2026Review
- Functional Biomaterials and 3D Bioprinting Approaches for Temporomandibular Joint Reconstruction: A Narrative Review.Journal of functional biomaterials · 2026Review
- Genetic Modulation of Wound Healing Pathways and Postoperative Risk in Plastic and Reconstructive Surgery: A Cohort Study.Journal of clinical medicine · 2026Article
- An Evaluation of Osseointegration Outcomes Around Trabecular Metal Implants in Human Maxillaries Reconstructed with Allograft and Platelet-Rich Fibrin.Biomimetics (Basel, Switzerland) · 2025Article
- Mesenchymal Stem Cells in Oral and Maxillofacial Surgery: A Systematic Review of Clinical Applications and Regenerative Outcomes.Journal of clinical medicine · 2025Review
- Impacts of Circular RNAs on the Osteogenic Differentiation of Dental Stem Cells.Stem cells international · 2025Review
- Optimization and Implication of Adipose-Derived Stem Cells in Craniofacial Bone Regeneration and Repair.Bioengineering (Basel, Switzerland) · 2024Review
- Impact of compression forces on different mesenchymal stem cell types regarding orthodontic indication.Stem cells translational medicine · 2024Article
- Amino Acid-Based Poly(ester urea) Biodegradable Membrane for Guided Bone Regeneration.ACS applied materials & interfaces · 2024Article
- The Biocompatibility and the Effect of Titanium and PEKK on the Osseointegration of Customized Facial Implants.Materials (Basel, Switzerland) · 2024Article
- Tissue-engineered tracheal implants: Advancements, challenges, and clinical considerations.Bioengineering & translational medicine · 2024Review
- The current techniques in dorsal augmentation rhinoplasty: a comprehensive review.Maxillofacial plastic and reconstructive surgery · 2024Review
- Bioactive injectable mucoadhesive thermosensitive natural polymeric hydrogels for oral bone and periodontal regeneration.Frontiers in bioengineering and biotechnology · 2024Review
- Resorbable GBR Scaffolds in Oral and Maxillofacial Tissue Engineering: Design, Fabrication, and Applications.Journal of clinical medicine · 2023Review
- An injectable and thermosensitive hydrogel with nano-aided NIR-II phototherapeutic and chemical effects for periodontal antibacteria and bone regeneration.Journal of nanobiotechnology · 2023Article
- The effect of green synthesis of TiOVeterinary medicine and science · 2023Article
- MIH and Dental Caries in Children: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2023Review
- Effect of inter-dental abutment distance on the impression accuracy of digital and conventional methods.Journal of medicine and life · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Craniofacial deformities (CFDs) develop following oncological resection, trauma, or congenital disorders. Trauma is one of the top five causes of death globally, with rates varying from country to country. They result in a non-healing composite tissue wound as they degenerate in soft or hard tissues. Approximately one-third of oral diseases are caused by gum disease. Due to the complexity of anatomical structures in the region and the variety of tissue-specific requirements, CFD treatments present many challenges. Many treatment methods for CFDs are available today, such as drugs, regenerative medicine (RM), surgery, and tissue engineering. Functional restoration of a tissue or an organ after trauma or other chronic diseases is the focus of this emerging field of science. The materials and methodologies used in craniofacial reconstruction have significantly improved in the last few years. A facial fracture requires bone preservation as much as possible, so tiny fragments are removed initially. It is possible to replace bone marrow stem cells with oral stem cells for CFDs due to their excellent potential for bone formation. This review article discusses regenerative approaches for different types of craniofacial diseases.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.