Evidence map›Paper›PMID 36926251›Full record

ArticleChronic diseases and translational medicine2023

Determinants of survival outcomes among esophageal cancer patients at a national referral hospital in Kenya.

Amsalu Degu, Peter N Karimi, Sylvia A Opanga, David G Nyamu

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Article in Chronic diseases and translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Amsalu DeguDepartment of Pharmaceutics and Pharmacy Practice, School of Pharmacy and Health Sciences United States International University-Africa Nairobi Kenya.ORCID 0000-0002-6562-0548
Peter N KarimiDepartment of Pharmacy, Faculty of Health Sciences University of Nairobi Nairobi Kenya.
Sylvia A OpangaDepartment of Pharmacy, Faculty of Health Sciences University of Nairobi Nairobi Kenya.
David G NyamuDepartment of Pharmacy, Faculty of Health Sciences University of Nairobi Nairobi Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The overall 5-year survival rate for esophageal cancer patients in low- and middle-income countries was reported to be low, despite the availability of advanced treatments. Thus, this study aimed to assess determinants of survival outcomes among esophageal cancer patients in Kenya. Methods: A retrospective cohort study was employed among 299 adult esophageal cancer patients. The data were collected using a data abstraction tool consisting of patients' clinical characteristics and survival outcome measuring parameters. Statistical Package for the Social Sciences (SPSS) statistical software (version 20.0, IBM. USA) was used to analyze the data. The Kaplan-Meier and Cox regression analyses were used to determine the survival outcome and determinants of mortality, respectively. Results: The mortality rate was 43.1%, and 11.1% of patients demonstrated distant metastases in the follow-up period. Despite treatment, 20.1% had progressed disease, and 13.0% did not respond to treatment. Radiotherapy (AHR: 3.3, 95% CI: 1.4-7.8, Conclusions: There was a high mortality rate, disease progression, and nonresponse of esophageal cancer patients. Hence, it is essential to improve the survival of patients through early detection and timely initiation of the available treatment options.

Indexed as

determinantsesophageal cancermortalitysurvival outcomes

Identifiers

PMID36926251
PMCPMC10011667

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.