Evidence map›Paper›PMID 36926241›Full record

ArticleWorld journal of hepatology2023

Hospitalizations for alcoholic liver disease during the COVID-19 pandemic increased more for women, especially young women, compared to men.

John Patterson Campbell, Vinay Jahagirdar, Adel Muhanna, Kevin F Kennedy, John H Helzberg

Open access · diamondAbstract read
In one paragraph

Article in World journal of hepatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Gender disparity in access to early liver transplant among patients with alcohol associated liver disease and limited sobriety is mediated by psychosocial factors.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

John Patterson CampbellDepartment of Internal Medicine, Division of Gastroenterology and Hepatology, Saint Luke's Health System of Kansas City and the University of Missouri-Kansas City, Kansas City, MO 64111, United States. jpc6nf@umsystem.edu.
Vinay JahagirdarDepartment of Internal Medicine, Saint Luke's Health System of Kansas City and the University of Missouri-Kansas City, Kansas City, MO 64111, United States.
Adel MuhannaDepartment of Internal Medicine, Division of Gastroenterology and Hepatology, Saint Luke's Health System of Kansas City and the University of Missouri-Kansas City, Kansas City, MO 64111, United States.
Kevin F KennedyDivision of Cardiology, Saint Luke's Health System of Kansas City, Kansas City, MO 64111, United States.
John H HelzbergDepartment of Internal Medicine, Division of Gastroenterology and Hepatology, Liver Disease Management Unit, Saint Luke's Health System of Kansas City and the University of Missouri-Kansas City, Kansas City, MO 64111, United States.
Saint Luke's Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlcoholic liver disease (ALD) remains one of the major indications for liver transplantation in the United States and continues to place a burden on the national healthcare system. There is evidence of increased alcohol consumption during the coronavirus disease 2019 (COVID-19) pandemic, and the effect of this on the already burdened health systems remains unknown.

aimTo assess the trends for ALD admissions during the COVID-19 pandemic, and compare it to a similar pre-pandemic period.

methodsThis retrospective study analyzed all admissions at a tertiary health care system, which includes four regional hospitals. ALD admissions were identified by querying a multi-hospital health system's electronic database using ICD-10 codes. ALD admissions were compared for two one-year periods; pre-COVID-19 from April 2019 to March 2020, and during-COVID-19 from April 2020 to March 2021. Data were analyzed using a Poisson regression model and admission rates were compared using the annual quarterly average for the two time periods, with stratification by age and gender. Percent increase or decrease in admissions from the Poisson regression model were reported as incident rate ratios.

resultsOne thousand three hundred and seventy-eight admissions for ALD were included. 80.7% were Caucasian, and 34.3% were female. An increase in the number of admissions for ALD during the COVID-19 pandemic was detected. Among women, a sharp rise (33%) was noted in those below the age of 50 years, and an increase of 22% in those above 50 years. Among men, an increase of 24% was seen for those below 50 years, and a 24% decrease in those above 50 years.

conclusionThe COVID-19 pandemic has had widespread implications, and an increase in ALD admissions is just one of them. However, given that women are often prone to rapid progression of ALD, this finding has important preventive health implications.

Indexed as

Alcoholic hepatitisAlcoholic liver cirrhosisAlcoholic liver diseaseAlcoholismAlcohol-related disordersCOVID-19PandemicYoung women

Identifiers

PMID36926241
PMCPMC10011902
OpenAlexW4321786481

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.