Evidence map›Paper›PMID 36926230›Full record

ArticleWorld journal of hepatology2023

Diabetes mellitus is not associated with worse short term outcome in patients older than 65 years old post-liver transplantation.

Saad Alghamdi, Shaden Alamro, Dhari Alobaid, Elwy Soliman, Ali Albenmousa, Khalid Ibrahim Bzeizi, Saleh Alabbad, Saleh A Alqahtani, Dieter Broering, Waleed Al-Hamoudi

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Article in World journal of hepatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Saad AlghamdiLiver and Small Bowel Health Centre Department, KFSHRC, Riyadh 11211, Saudi Arabia. mdisaad@kfshrc.edu.sa.
Shaden AlamroDepartment of Medicine, KFSHRC, Riyadh 11211, Saudi Arabia.
Dhari AlobaidDepartment of Medicine, KFSHRC, Riyadh 11211, Saudi Arabia.
Elwy SolimanLiver and Small Bowel Health Centre Department, KFSHRC, Riyadh 11211, Saudi Arabia.
Ali AlbenmousaLiver and Small Bowel Health Centre Department, KFSHRC, Riyadh 11211, Saudi Arabia.
Khalid Ibrahim BzeiziLiver and Small Bowel Health Centre Department, KFSHRC, Riyadh 11211, Saudi Arabia.
Saleh AlabbadLiver and Small Bowel Health Centre Department, KFSHRC, Riyadh 11211, Saudi Arabia.
Saleh A AlqahtaniLiver and Small Bowel Health Centre Department, KFSHRC, Riyadh 11211, Saudi Arabia.
Dieter BroeringLiver and Small Bowel Health Centre Department, KFSHRC, Riyadh 11211, Saudi Arabia.
Waleed Al-HamoudiLiver and Small Bowel Health Centre Department, KFSHRC, Riyadh 11211, Saudi Arabia.
King Fahd Security College · SAAlfaisal University · SAJohns Hopkins University · USKing Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-alcoholic fatty liver disease is a global health care challenge and a leading indication of liver transplantation (LT). Hence, more patients with diabetes mellitus (DM) are undergoing LT, especially, above the age of 65.

aimTo evaluate the impact of DM on short-term outcomes post-LT in patients over the age of 65.

methodsWe collected data of patients who underwent LT from January 2001 until December 2019 using our electronic medical record. We assessed the impact of DM on short-term outcomes, one-year, post-LT based on the following variables: Survival at one year; acute cellular rejection (ACR) rates; intensive care unit (ICU) and hospital length of stay; and readmissions.

resultsTotal of 148 patients who are 65 year or older underwent LT during the study period. The mean age is 68.5 ± 3.3 years and 67.6% were male. The median Model for End-stage Liver Disease score at time of transplantation was 22 (6-39), 39% of patients had hepatocellular carcinoma and 77.7% underwent living donor LT. The one-year survival was similar between DM patients and others, 91%. ACR occurred in 13.5% of patients (

conclusionThe short-term outcome of elderly diabetic patients undergoing LT is similar to others. The presence of DM in elderly LT candidates should not discourage physicians from transplant consideration in this cohort of patients.

Indexed as

Acute cellular rejectionDiabetes mellitusElderlyGraft survivalLiver transplantation

Identifiers

PMID36926230
PMCPMC10011905
OpenAlexW4321786458

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.