Evidence map›Paper›PMID 36926194›Full record

ArticleFrontiers in physiology2023

Hypoxia enhances interactions between Na

Julie M Lade, Manuella R Andrade, Clark Undem, Jasmine Walker, Haiyang Jiang, Xin Yun, Larissa A Shimoda

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Julie M LadeDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Baltimore, MD, United States.
Manuella R AndradeDepartment of Physiology, Johns Hopkins School of Medicine, Baltimore, MD, United States.
Clark UndemDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Baltimore, MD, United States.
Jasmine WalkerDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Baltimore, MD, United States.
Haiyang JiangDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Baltimore, MD, United States.
Xin YunDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Baltimore, MD, United States.
Larissa A ShimodaDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Baltimore, MD, United States.
Pulmonary and Critical Care Associates · USJohns Hopkins University · US

Funding

Na+/H+ exchange in pulmonary hypertensionR01HL073859 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI SHIMODA, LARISSA A. · 2003 to 2020
$4.2M
Short-Term Training Program to Increase Diversity in Health-Related ResearchR25HL084762 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI DAMARLA, MAHENDRA, SHIMODA, LARISSA A. · 2006 to 2024
$2.1M
NHLBI NIH HHS R01 HL073859NHLBI NIH HHS R25 HL084762
6 · The paper itself

Abstract

Exposure to hypoxia, due to high altitude or chronic lung disease, leads to structural changes in the pulmonary vascular wall, including hyperplasia and migration of pulmonary arterial smooth muscle cells (PASMCs). Previous studies showed that hypoxia upregulates the expression of Na

Indexed as

hypoxialungpulmonary hypertensionsmooth musclesmooth muscle actin

Identifiers

PMID36926194
PMCPMC10011449
OpenAlexW4323310000

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read72
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.