Evidence map›Paper›PMID 36926157›Full record

ArticleTurk gogus kalp damar cerrahisi dergisi2023

Prognostic factors and the prognostic role of inflammation indices in malignant pleural mesothelioma.

Senar Ebinç, Zeynep Oruç, Ziya Kalkan, Oğur Karhan, Zuhat Urakçı, Mehmet Küçüköner, Muhammet Ali Kaplan, Işıkdoğan Abdurrahman

Abstract read
In one paragraph

Article in Turk gogus kalp damar cerrahisi dergisi, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Senar EbinçDepartment of Internal Medicine, Division of Medical Oncology, Dicle University Faculty of Medicine, Diyarbakır, Türkiye.
Zeynep OruçDepartment of Internal Medicine, Division of Medical Oncology, Dicle University Faculty of Medicine, Diyarbakır, Türkiye.
Ziya KalkanDepartment of Internal Medicine, Division of Medical Oncology, Dicle University Faculty of Medicine, Diyarbakır, Türkiye.
Oğur KarhanDepartment of Internal Medicine, Division of Medical Oncology, Dicle University Faculty of Medicine, Diyarbakır, Türkiye.
Zuhat UrakçıDepartment of Internal Medicine, Division of Medical Oncology, Dicle University Faculty of Medicine, Diyarbakır, Türkiye.
Mehmet KüçükönerDepartment of Internal Medicine, Division of Medical Oncology, Dicle University Faculty of Medicine, Diyarbakır, Türkiye.
Muhammet Ali KaplanDepartment of Internal Medicine, Division of Medical Oncology, Dicle University Faculty of Medicine, Diyarbakır, Türkiye.
Işıkdoğan AbdurrahmanDepartment of Internal Medicine, Division of Medical Oncology, Dicle University Faculty of Medicine, Diyarbakır, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In this study, we aimed to investigate the prognostic factors of malignant pleural mesothelioma and the prognostic value of inflammation indices in malignant pleural mesothelioma. Methods: Between January 2002 and December 2019, a total of 132 patients (74 males, 58 females; mean age: 55 years; range, 31 to 79 years) diagnosed with malignant pleural mesothelioma were retrospectively analyzed. Patients" demographic data and laboratory results were recorded. The prognostic value of the following five inflammation indices was evaluated: neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, advanced lung cancer inflammation index, C-reactive protein/albumin ratio, and prognostic nutritional index. Results: Of all patients, 81% (n=107) were aged 65 or older and 61.4% (n=81) had an epithelioid histology. Of 12 variables examined in the multivariate analysis for their relationship with survival, age ≥65 years, non-epithelioid subtype, and prognostic nutritional index <40 were found to be poor prognostic factors. Based on the score constructed from these factors, the good prognostic group (score 0-1) had a median overall survival of 21 months and a one-year survival rate of 77.9%, while the poor prognostic group (score 2-3) had a median overall survival of nine months and a one-year survival rate of 29.7%. Conclusion: Our study results indicate that age ≥65 years, prognostic nutritional index <40, and non-epithelioid histological subtype are poor prognostic factors of malignant pleural mesothelioma.

Indexed as

Inflammation indicesmalignant pleural mesotheliomaprognostic nutritional indexprognostic score

Identifiers

PMID36926157
PMCPMC10012989

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