Evidence map›Paper›PMID 36926053›Full record

ArticleJournal of Taibah University Medical Sciences2023

The severity of COVID-19 in hypertensive patients is associated with mirSNPs in the 3' UTR of

Muhammad Safdar, Mehmet Ozaslan, Rebaz M Mustafa, Shukur W Smail, Samiha S Khan, Muhammad Sajjad Khan, Muhammad Asad Akhtar, Hafiz Khawar Ali, Umair Younas, Muhammad Saeed and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Taibah University Medical Sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 6 countries.

Muhammad SafdarDepartment of Breeding and Genetics, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan.
Mehmet OzaslanDepartment of Biology, Division of Molecular Biology and Genetics, Gaziantep University, Gaziantep, Turkey.
Rebaz M MustafaDepartment of Chemistry, Faculty of Science and Health, Koya University, Koya KOY45, Kurdistan Region - F.R. Iraq.
Shukur W SmailDepartment of Biology, College of Science, Salahaddin University-Erbil, Erbil, Iraq.
Samiha S KhanUniversity Medical and Dental College Faisalabad, Pakistan.
Muhammad Sajjad KhanCholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan.
Muhammad Asad AkhtarCardiovascular Research Group, Dept. Medical Biology, UiT-The Arctic University of Norway, Tromsø, Norway.
Hafiz Khawar AliDepartment of Molecular Biology, Virtual University of Pakistan, Lahore, Pakistan.
Umair YounasDepartment of Livestock Management, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan.
Muhammad SaeedDepartment of Poultry Science, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan.
Faisal SiddiqueDepartment of Microbiology, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan.
Muhammad NaveedDepartment of Clinical Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing, P.R China.
SaifUr RehmanState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources of Guangxi University, Nanning, China.
University of Veterinary and Animal Sciences · PKGaziantep University · TRKoya University · IQNanjing Medical University · CNPunjab Medical College · PKSalahaddin University-Erbil · IQState Key Laboratory For Conservation and Utilization of Subtropical Agro-BioresourcesUiT The Arctic University of Norway · NOVirtual University of Pakistan · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The SARS-CoV-2 virus targets the antigen converting enzyme 2 ( Objectives: This study aimed to identify the association between increased susceptibility and severity in order to evaluate their impact in hypertensive COVID-19 patients using in vitro and in silico models. Methods: We identified 80 miRNA binding sites on Results: Interestingly, the binding site of miR-3658 corresponding to the 3' UTR of Conclusion: The identified SNPs could represent potential informative signatures owing to their position in the splicing site of the

Indexed as

3′ UTRACE2COVID-19HypertensionmiRNAsSeverity

Identifiers

PMID36926053
PMCPMC9981452
OpenAlexW4323044804

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.