Evidence map›Paper›PMID 36926036›Full record

ArticleFrontiers in endocrinology2023

Four missense genetic variants in

Nicoline Uglebjerg, Fariba Ahmadizar, Dina M Aly, Marisa Cañadas-Garre, Claire Hill, Annemieke Naber, Asmundur Oddsson, Sunny S Singh, Laura Smyth, David-Alexandre Trégouët and 13 more

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Observational
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 11 institutions in 8 countries.

Nicoline UglebjergComplications Research, Steno Diabetes Center Copenhagen, Herlev, Denmark.
Fariba AhmadizarDepartment of Epidemiology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, Netherlands.
Dina M AlyDepartment of Clinical Sciences, Lund University, Malmö, Sweden.
Marisa Cañadas-GarreCentre for Public Health, Queen's University Belfast, Belfast, United Kingdom.
Claire HillCentre for Public Health, Queen's University Belfast, Belfast, United Kingdom.
Annemieke NaberDepartment of Internal Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, Netherlands.
Asmundur OddssondeCODE Genetics, Amgen, Inc., Reykjavik, Iceland.
Sunny S SinghDepartment of Internal Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, Netherlands.
Laura SmythCentre for Public Health, Queen's University Belfast, Belfast, United Kingdom.
David-Alexandre TrégouëtUniversity of Bordeaux, Institut National de la Santé et de la Recherche Médicale (INSERM), Bordeaux Population Health Research Center, Bordeaux, France.
Layal ChakerDepartment of Epidemiology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, Netherlands.
Mohsen GhanbariDepartment of Epidemiology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, Netherlands.
Valgerdur SteinthorsdottirdeCODE Genetics, Amgen, Inc., Reykjavik, Iceland.
Emma AhlqvistDepartment of Clinical Sciences, Lund University, Malmö, Sweden.
Samy HadjadjNantes Université, Centre Hospitalier Universitaire Nantes, Centre National de la Recherche Scientifique, INSERM, l'institut du thorax, Nantes, France.
Mandy Van HoekDepartment of Internal Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, Netherlands.
Maryam KavousiDepartment of Epidemiology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, Netherlands.
Amy Jayne McKnightCentre for Public Health, Queen's University Belfast, Belfast, United Kingdom.
Eric J SijbrandsDepartment of Internal Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, Netherlands.
Kari StefanssondeCODE Genetics, Amgen, Inc., Reykjavik, Iceland.
Matias SimonsInstitute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany.
Peter RossingComplications Research, Steno Diabetes Center Copenhagen, Herlev, Denmark.
Tarunveer S AhluwaliaComplications Research, Steno Diabetes Center Copenhagen, Herlev, Denmark.
Erasmus MC · NLdeCODE Genetics (Iceland) · ISQueen's University Belfast · GBLund University · SESteno Diabetes Center · DKBordeaux Population Health · FRHeidelberg University · DEInserm · FRPfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research · ESUniversity Medical Center Utrecht · NLUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Rare genetic variants in the Methods: We carried out a genetic association-based linear regression analysis between four Results: Albeit we did not observe associations between eGFR Conclusions: The positive associations between the four

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2Receptors, Cell SurfaceRenal Insufficiency, ChronicAlbuminsAlbuminuriaCreatinineCystatin CEuropean PeopleGenetic Association StudiesGlomerular Filtration RateHumansProteinuriaAlbuminsCreatinineCystatin Cintrinsic factor-cobalamin receptorReceptors, Cell Surfacechronic kidney disease (CKD)cubilinCUBNdiabeteseGFRgeneticskidney functionnon-diabetes

Identifiers

PMID36926036
PMCPMC10011651
OpenAlexW4323309932

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read2
measurements read26
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.